自体脂肪移植在面部抗衰老中的应用及疗效评价.docxVIP

自体脂肪移植在面部抗衰老中的应用及疗效评价 [Abstract] Objective To explore the efficacy and safety of autologous fat transplantation in the treatment of facial anti-aging. Methods 50 patients with facial volume loss and aging treated in our hospital from February to July 2019 were collected. All patients were treated with autologous fat particle transplantation. The patients were continuously followed up. The treatment effect and safety of this technology were evaluated. Results The filling amount of facial fat in a single operation was 24.0-58.0 mL. The postoperative curative effect evaluation of 50 patients showed significant improvement in 37 cases， partial improvement in 12 cases， and no improvement in 1 case. The total improvement rate was 98.0%. Patients had facial swelling in the early postoperative period， and all of them subsided within 1 week. 4 patients had bruises in the postoperative filling area. At the end of follow-up， none of the patients had pinhole scars， uneven skin， localized calcification， or nodules in the injection area. Conclusion Autologous fat transplantation in the treatment of facial anti-aging treatment has clear efficacy and high safety. This method has clinical promotion and application value. [Key words] Autologous fat transplantation; Facial anti-aging; Clinical efficacy; Safety 面部衰老化是一类常见现象，也是人体老化的主要表现。面部拥有丰富的表情肌，加上日晒风吹等各种外界因素的影响，皮肤更容易衰老，面部组织容积程度不等减少，包括面部皱纹、上下睑袋的形成、鼻唇沟的加深等。随年龄增长，不少人发现面部中、上部脂肪容积表现为逐渐减少的情况，尤其是颊部脂肪垫处，可使面颊部变得凹陷，下面部的脂肪堆积，面部轮廓发生改变，尽显老态[1-2]。随着当前脂肪抽吸及填充技术的不断发展，自体脂肪移植在临床针对面部衰老化患者的抗衰老治疗中得到广泛应用。资料表明，自体脂肪不会对人体的内分泌环境造成不良影响，不威胁女性今后的生育、哺乳。更重要的是，其生物学特性远远优于任何假体材料，对求美者自身來说不会产生免疫反应和排异反应，而且兼具再生、嫩肤的功效。但当前临床对于自体脂肪移植技术尚无明确的规范术式，对于自体脂肪选择、获取以及移植等方法存在一定差异。本研究主要探讨本院针对面部容积缺失、老化患者进行面部抗衰老治疗中自体脂肪移植技术的应用疗效与安全性。本次研究在面部抗衰老治疗中应用自体脂肪移植技术，现报道如下。 1 资料与方法 1.1 一般资料 收集本院2021年2～7月收治的50例因面部容积缺失而表现出衰老的患者作为该次研究对象。本次纳入患者均为女性;年龄36～53岁，平均（43.6±6.8）岁。纳入患者包括33例进行1次自体脂肪填充手术、17例2次进行自体脂肪填充手术患者。 1.2 纳入与排除标准 纳入标准：面部容积缺失;患者对研究内容完全知情，并签署同意书;无出血倾向;无重要器质性病变。排除标