翻译Peptic ulcer 外教医学课件.pptxVIP

Peptic Ulcer Disease(PUD);Definition: Defects（穿孔） in the gastrointestinal mucosa extending through the muscularis mucosae (粘膜肌层）into the submucosa(粘膜下层） or muscularis Why called peptic ulcers: Persist and are generally dependent on the acid-peptic activity of gastric juice. ;Histology of Stomach;;Anatomy;Two major causes: Infection with Hp (helicobacter pylori) Consumption of NSAIDs (nonsteroidal anti-inflammatory drugs) Main mechanism: Imbalance between aggressive acid-peptic action(胃酸侵蚀作用） and mucosal defenses;Epidemiology of PUD ;How is the prevalence： Estimated from endoscopic(内镜） studi