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* s * * * (General Introduction) 2004 Spring Teacher:毕黎琦 Rheumatology Section 1 General Introduction(总论) of Rheumatic Diseases Requirements(要求):1. To know (了解)the definition of rheumatic diseases and its common pathology. 2. To be familiar with (熟悉)the classification of rheumatic diseases and the common characteristics of connective tissue diseases. 3. To grasp(掌握) the features of joint manifestation of rheumatic diseases and clinical importance (意 义)of auto-antibodies detection.4. To be familiar with(熟悉) the classification and mechanism of 3 kinds of anti-rheumatic drugs. Definition: 1、Rheumatism (风湿):It’s defined as the chronic pain of joint, peri-articular tissues,muscle and bone. (风湿:是指关节、关节周围软组织、肌肉、 骨出现的慢性疼痛。) 2、Rheumatic diseases(风湿性疾病): It’s a disease entity involving joints and peri-articular tissues with different causes.(风湿性疾病:是指一大类病因各不相同,但均累及 关节及其周围组织的疾病。) It encompasses diffuse connective tissue diseases, and other disorders involving joints and peri-articular tissues (including muscle,tendon, ligament, etc).(它包括:弥漫性结 缔组织病及各种病因引起的关节和关节周围软组织,包括肌、 肌腱、韧带等的疾病。 概念: 3、 diffuse connective tissue disease(弥漫性结缔组织病), 简称结缔组织病(CTD). It’s the main kind of rheumatic diseases. It belongs to organ nonspecific autoimmune diseases(器官非特异性自身免疫病). It’s also called collagenic disease(胶原病). Common characters of diffuse CTD: (1)pathogenesis :autoimmunity; (2)pathologic change :chronic inflammation of vessels and connective tissue; (3)multis
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