板蓝根对机体免疫功能及流感病毒FM1的作用.docVIP

板蓝根对机体免疫功能及流感病毒FM1的作用 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：板蓝根对机体免疫功能及流感病毒FM1的作用 1 1 器材 3 2 方法 3 3 结果 6 4 讨论 7 文2：板蓝根对机体免疫功能及流感病毒FM1的作用 8 1 器材 9 2 方法 10 3 结果 12 4 讨论 13 参考文摘引言： 15 原创性声明（模板） 16 文章致谢（模板） 17 正文 板蓝根对机体免疫功能及流感病毒FM1的作用 文1：板蓝根对机体免疫功能及流感病毒FM1的作用 Abstract：ObjectiveTo study the strengthening function of extract of Radix Isatidis on immune system in Kunming mice and its antiviral effects on influenza virus (FM1). MethodsExtract of Radix isatidis was intraperitoneally injected to Kunming mice. Lymphocyte proliferation assay and rosette formation test were used to measure the cellular immune function and humoral immune function and erythrocytic immune adhesive function of mice. FM1 virus was dropped nasally in Kunming mice, then the animals were control intraperitoneally injected extract of Radix isatidis, the antiviral effects of Radix isatidis were with control group,spleen index in the Radix Isatidis group increased（F=, P ＜）. Compared with control group, SI of T lymphocyte in the Radix Isatidis group increased significantly（F=, P ＜）, SI of B lymphocyte increased obviously（F=, P ＜）, and the rate of RBCC3bR was increased（F=, P ＜）, too. Compared with control group the rate of RBCIC in the Radix Isatidis group decreased greatly（F=, P ＜）. Compared with negative group, Lung index in the Radix Isatidis group decreased（F=, P ＜）. The degree of change in weight of that group was higher than negative group（F=, P ＜）. ConclusionRadix Isatidis has strong strengthening function on immune system in Kunming mice, its enhancing function on red cell immune adherence (RCIA) is extremely significant. Moreover，it also has antiviral effects on influenza virus. Key words：Radix Isatidis; Influenza virus; Lymphocyte; RCIA; Antiviral effects 中药板蓝根为十字花科菘蓝属植物菘蓝Isatis indigotica Fort.的根，性寒味苦，有清热解毒、凉血消肿的功效。随着国际上应用天然药物的热潮，板蓝根的药理活性及其有效成分得到了深入的研究，并引起了国内外学者的广泛关注，但是关于板蓝根制剂对红细胞免疫功能的作用却少有报道。1981年美国的Siegel［1，2］在前人研究的基础上提出了“红细胞免疫系统(RCIS)”的新概念。近20多年来国内