黑芝麻油对动脉粥样硬化兔血脂和主动脉形态学的影响.docVIP

黑芝麻油对动脉粥样硬化兔血脂和主动脉形态学的影响 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：黑芝麻油对动脉粥样硬化兔血脂和主动脉形态学的影响 1 1 材料与方法 2 2 结果 3 3 讨论 4 文2：氯沙坦对兔动脉粥样硬化的影响 5 1 材料和方法 6 2 实验结果 7 3 讨论 7 参考文摘引言： 8 原创性声明（模板） 9 文章致谢（模板） 10 正文 黑芝麻油对动脉粥样硬化兔血脂和主动脉形态学的影响 文1：黑芝麻油对动脉粥样硬化兔血脂和主动脉形态学的影响 Effects of Black Sesame Oil on the Blood Lipid and the Pathologic Chang of Arteria Aorta in Rabbit of Atherosclerosis Abstract:ObjectiveTo observe the effects of black sesame oil on the blood lipid and the pathologic chang of artery in rabbit of rabbits were randomly divided into 3 groups:basic fodder group,cholesterol fodder group,black sesame oil were 10 rabbits in each difference fodder for 20 weeks,the contents of totalcholesterol(TC), low deity lipoprotein cholesterol(LDL-C),high deity lipoprotein cholesterol(HDL-C),triglyceride(TG) in serum of rabbits were determined .The pathologic chang of artery was contents of TC and LDL-C in the cholesterol fodder group were significantly higher than the basic fodder group（P）. The contents of TC and LDL-C in black sesame oil group were significantly lower than the cholesterol fodder group（P）.In black sesame oil group the pathologic chang of arteria aorta endomembrane was significantly lighter than that in the cholesterol fodder black sesame oil decreases the blood lipid of atherosclerosis rabbits and shows the function of vanishing fuction may be resulted by the uaturated fatty acid and antioxidant fraction of black sesame oil. Key words:Black sesame oil; atherosclerosis; Totalcholesterol; Low deity lipoprotein cholesterol 心脑血管疾病是目前严重威胁人类健康的首位原因，而动脉粥样硬化是心脑血管疾病的主要病理基础，因此预防和 治疗 动脉粥样硬化就显得尤其重要。本实验以基础饲料组和高脂饲料组为对照，观察黑芝麻油对动脉粥样硬化兔模型的血脂变化和主动脉形态学改变的影响，并对其机制进行探讨。 1 材料与方法 动物采用健康的大白耳兔30只，体重~ kg，雌雄不限，自由饮水，由吉林大学基础医学院动物中心提供。将大白耳兔随机分成3个组：基础饲料组、高脂饲料组、黑芝麻油组，每组10只。 动物饲养方法基础饲料组1~20周，饲喂基础饲料。高脂饲料组1~15周，饲喂基础饲料加胆固醇（每只 g /d）；16~20周，饲喂基础饲料。黑芝麻油组1~5周，饲喂基础饲料加胆固醇（每只 g /d）；6~15周，饲喂基础饲料加胆固醇（每只 g/ ）和黑芝麻油（每只 g /d）；16~20周，饲喂基础饲料加黑芝麻油（每只 g /d）。第20周末，采血后将全部实验动物处死，取组织标本。 观