多肿瘤标志物的联合检测和分析对胰腺癌诊断的价值探讨临床医学.docVIP

多肿瘤标志物的联合检测和分析对胰腺癌诊断的价值探讨临床医学 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：多肿瘤标志物的联合检测和分析对胰腺癌诊断的价值探讨临床医学 1 1 资料和方法 3 2 结果 4 3 讨论 5 文2：血清CA199CEACA125CY211联合检测对于胰腺癌诊断的临床价值 7 1 资料与方法 7 2 结果 8 2. 2 血清中的各项目诊断价值比较 见表2。 8 3 讨论 8 参考文摘引言： 10 原创性声明（模板） 11 文章致谢（模板） 12 正文 多肿瘤标志物的联合检测和分析对胰腺癌诊断的价值探讨临床医学 文1：多肿瘤标志物的联合检测和分析对胰腺癌诊断的价值探讨临床医学 Clinical significance of 12 tumor marke detection using protein biochip in the diagnosis of pancreaticcarcinomaXia Feng， Zheng Ji， Wang Shuguang，Dong Jiahong. Ititute of Hepatobiliary Surger-y Southwest Hospital， Third Military Medical Univeity， Chongqing 400038， China 【Abstract】 ObjectiveTo discuss the clinical significance of multi-tumor marke detection usingprotein biochip in the diagnosis of pancreatic carcinoma. Methods12 serum tumor marke （CA19-9，CEA， CA242， β-HCG， AFP， Free-PSA， Ferritin， E， PSA， CA125， CA15-3 and HGH） in 81 pa-tients with pancreatic carcinoma， 57 patients with benign pancreatic disease and 547 healthy volunteewere detected by using Protein Chip. ResultsThere was significant difference in the expression of the 12tumor marke among the three groups. The expression of tumor marke CA19-9， CEA， CA242，β-HCG， AFP， CA125 and HGH in the carcinoma group was markedly stronger than in the benign group（P）， and the same as the positive rate of tumor marke CA19-9， CEA， CA242， Ferritin，β-HCG， AFP， CA125， HGH and CA15-3 （P）. The seitivity of CA242， CA19-9， CEA andCA125 for pancreatic carcinoma was more than 50%， the specificity was more than 70%， and the validitywas also more than 60%. CA242 is the tumor marker with the highest seitivity， specificity and validityof %， % and %， respectively. The seitivity and validity of combined detection ofCA242， CA19-9 and CEA were improved. The validity of combined detection of two of the three markewas more than %， and that of the three marke reached %. ConclusioCombined detectionof CA242， CA19-9 and CEA can improve the diagnosis of pancreatic carcinoma. 【Key words】pancr