不同气腹压对老年患者腹腔镜胆囊切除术后肝功能的影响临床医学.docVIP

不同气腹压对老年患者腹腔镜胆囊切除术后肝功能的影响临床医学 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：不同气腹压对老年患者腹腔镜胆囊切除术后肝功能的影响临床医学 1 1 资料和方法 3 2 结果 4 3 讨论 4 文2：手术体位对腹腔镜胆囊切除术肝功能的影响 6 1 资料与方法 7 2 结果 8 参考文摘引言： 10 原创性声明（模板） 11 文章致谢（模板） 12 正文 不同气腹压对老年患者腹腔镜胆囊切除术后肝功能的影响临床医学 文1：不同气腹压对老年患者腹腔镜胆囊切除术后肝功能的影响临床医学 Changes of hepatic function in elderly patients undergone laparoscopic cholecystectomy in respoe to different pneumoperitoneum pressure FU Yishan, LIU Haizhong, WANG Chun, GONG Jianping, GUO Juhong, WU Jun, ZHU Zhirun, LIAO Chaoxin. Department of Surgery, the Central Hospital of Xipeng, Chongqing 401326, China 【Abstract】 Objective To discuss the effect of different pneumoperitoneum pressure on changes of hepatic function in elderly patients treated with laparoscopic cholecystectomy (LC) and the corresponding mechanism. Methods A total of 76 patients at age over 60 yea treated with LC were divided into three groups, ie, low pneumoperitoneum pressure group (Group LP, n=20), standard pneumoperitoneum pressure group (Group SP, n=33) and high pneumoperitoneum pressure group (Group HP, n=23) based on intraoperative CO2 pneumoperitoneum pressure. During operation, the intra-abdominal pressure (IAP) remained at kPa in Group LP, kPa in Group SP and kPa in Group HP. In the meantime, according to maintenance of intraoperative pneumoperitoneum, Group SP was subdivided into two groups including Group A (50 min) and Group B (≤50 min). Then, the venous blood was collected at day 1 preoperatively and at days 1 and 4 postoperatively respectively to determine and compare the contents of alanine aminotraferase (ALT) and aspartate aminotraferase (AST) in all groups. Results At day 1 postoperatively, the contents of ALT and AST in Groups SP and HP were significantly increased (P), with more significant increase in Group SP (P) but iignificant increase in Group LP （P＞）. At day 4 postoperatively, blood serum ALT and AST in Group SP decreased nearly to normal level but that in Group HP