C反应蛋白在急性心肌梗死中的作用及其预测价值.docVIP

C反应蛋白在急性心肌梗死中的作用及其预测价值 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：C反应蛋白在急性心肌梗死中的作用及其预测价值 1 1 资料与方法 3 2 结果 4 3 讨论 4 文2：C反应蛋白对急性冠脉综合征预后的预测价值 7 1 对象与方法 7 2 结果 8 3 讨论 9 参考文摘引言： 10 原创性声明（模板） 11 文章致谢（模板） 12 正文 C反应蛋白在急性心肌梗死中的作用及其预测价值 文1：C反应蛋白在急性心肌梗死中的作用及其预测价值 ［Abstract］ Objective To investigate the relatiohip between the levels of plasma C-reactive protein（CRP）and acute myocardial infarction（AMI）.To observe the relatiohip between the levels of CRP and the major risk facto of （1）The hsCRP and CK concentratio were tested in 30 patients with acute myocardial infarction and in 30 cured patients on the 30th day of stable phase of AMI.（2）The hsCRP and CK concentratio were tested in 31 utable angina pectoris (UAP)，38 stable angina pectoris(SAP) and 40 normal peo (Nor).（3）To measure the values of white cell count in all （1）The plasma hsCRP concentratio were gradually increasing in Nor group，SAP group，UAP group，and AMI were significant differences each other except the hsCRP level of Nor group and SAP group.（2）The levels of hsCRP of patients with AMI in period of oet were significantly higher than those healthy adults（P＜）。The levels of hsCRP had no significant difference between cured patients on the 30th day of stable phase of AMI and healthy adults（P）.（3）Correlation analysis： There were positive relatiohips between hsCRP and white cell count，CK， The levels of hsCRP are gradually increasing according to the disease degrees and can be used as a predictor of the prognosis of is a new risk factor of AMI. ［Key words］ C-reactive protein；acute myocardial infarction；inflammation 急性心肌梗死（acute myocardial infarction,AMI）是一种多种机制共同作用的冠状动脉粥样硬化性疾病。其病理过程主要是动脉硬化、血管腔阻塞，导致了心肌细胞的缺血性坏死。近年来研究发现，炎症反应贯穿动脉粥样斑块的起始形成，炎症介质和脂类相互作用决定斑块破裂，因而炎症反应在AMI的病变中起着核心作用［1～3］。C反应蛋白(C-reactive protein,CRP)是由肝细胞合成的一种较为典型的急性期蛋白，是炎症的一个生物学标记物。本文旨在探讨CRP水平在动脉粥样硬化的发生、发展过程中的作用和AMI发生后的不同时段的变化及其预测价值。 1 资料与方法 一般资料 正常对照组为40例健康体检者，其中男22例，女18例，年龄31～70岁；平均（±）岁。其肝功能、肾功能、心电图均正常，无心血管病史和自身免疫性疾病、肿瘤、糖尿病或其他的感染