内科学教学课件515 白血病、淋巴瘤.pptVIP

Acute lymphoblastic leukemia (L2) bone marrow: the large lymphocytic blasts with large amount of cytoplasm. Irregular-shaped nuclei with large and visible nucleolus. Clinical features: Signssymptoms (1) General: 1. pallor, fatigue, weakness, palpitation, dyspnea on exertion (they reflect the rise of anemia) 2. Easy bruising, petechiae, epistaxis, gingival bleeding ( they reflect thrombocytopenia) 3. Fever is present in many patients at the time of diagnosis ( absolute neutrophil counts under 500/ul) 4. enlargement of the liver, spleen or lymphnodes Clinical features: Signssymptoms