RIRS联合EPVL治疗老年肾结石的临床研究.docVIP

第 PAGE 页 共 NUMPAGES 页 RIRS联合EPVL治疗老年肾结石的临床研究 【摘要】 目的：^察输尿管软镜钬激光碎石术（retrograde intrarenal surgery，RIRS）术后联合使用体外物理振动排石（external physical vibration lithecbole，EPVL）治疗老年肾结石的临床效果。方法：选取2021年3月-2021年3月福建省宁德市闽东医院收治的经RIRS术后存在残余肾结石的老年患者81例为研究对象，按随机对照分配法将其分为对照组（n=39）及观察组（n=42）。对照组使用多饮水加排石药物等保守治疗排石，观察组采用EPVL治疗。比较两组一般资料、术后血肌酐（serum creatinine，Scr）及中性粒细胞明胶酶相关载脂蛋白（neutrophil gelatinase-associated lipocalin，NGAL）、结石清除情况。结果：观察组术后7 d尿中见石率高于对照组，差异有统计学意义（P 0.05）。观察组术后7、14 d及术后1个月的结石排净率均明显高于对照组，差异均有统计学意义（P 0.05）。术后7 d，两组血Scr及血NGAL比较，差异均无统计学意义（P 0.05）。术后6 d，两组血尿、尿常规中白细胞阳性率比较，差异均无统计学意义（P 0.05）;术后14 d及术后1个月，观察组血尿、尿常规中白细胞阳性率均低于对照组，差异均有统计学意义（P 0.05）。两组患者均未发生严重并发症。结论：RIRS术后联合使用EPVL治疗老年肾结石的临床效果良好，安全有效，显著提高排石率。 【关键词】 尿石症 体外物理振动排石 输尿管软镜钬激光碎石术 Clinical Research of RIRS Combined with EPVL in the Treatment of Renal Calculi in Elderly Patients/HUANG Youfeng， CHEN Huihong， LIU Changming， WANG Xiaohong， HUANG Shulong， HUANG Xinghua. //Medical Innovation of China， 2021， 18（36）： 043-047 [Abstract] Objective： To observe the clinical effect of retrograde intrarenal surgery （RIRS） combined with external physical vibration lithecbole （EPVL） in the treatment of renal calculi in elderly patients. Method： A total of 81 elderly patients with residual kidney stones after RIRS surgery admitted to Mindong Hospital of Ningde City from March 2021 to March 2021 were selected as the research objects， and they were divided into control group （n=39） and observation group （n=42） according to the randomized controlled allocation method. The control group was treated with more drinking water and stone removal drugs， and the observation group was treated with EPVL. The general data， postoperative serum creatinine （Scr）， neutrophil gelatinase-associated lipocalin （NGAL） and stone clearance were compared between the two groups. Result： The urolithiasis rate in observation group was higher than that in control group 7 d after surgery， the difference was statistically significant （P 0.05）. The stone removal rate of the obser