重症感染CRRT策略.pptVIP

单中心/小样本研究 大多数研究显示：高容量RRT能改善sepsis预后 第三十一页，共四十四页。  150 patients with Septic Shock and Acute Kidney Injury Randomization  within 24 hours of ICU admission (! Early septic shock) 96 hours at 96 hours at 35 ml/kg/hour 70 ml/kg/hour Mortality rate at 28 days 60 days 90 days Any dose of vasopressors (Noradrenaline)Or 5μg/kg/m ofDopamine Oliguria 0.5 ml/kg/h creatinine X 2 RIFLE Injury IVOIRE hIgh VOlume in Intensive caRE 第三十二页，共四十四页。 Begining of 2009 : 140 patients included –Study Terminated Mortality at