坦索罗辛联合双氯芬酸钠在输尿管下段结石辅助排石中的作用（医疗卫生论文资料）.docVIP

坦索罗辛联合双氯芬酸钠在输尿管下段结石辅助排石中的作用（医疗卫生论文资料） 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：坦索罗辛联合双氯芬酸钠在输尿管下段结石辅助排石中的作用 1 1 资料与方法 3 2 结 果 4 3 讨 论 4 文2：坦索罗辛在输尿管下段结石体外震波碎石后辅助排石中的应用 6 1 资料与方法 6 2 结果 7 3 讨 论 7 参考文摘引言： 9 原创性声明（模板） 10 文章致谢（模板） 10 正文 坦索罗辛联合双氯芬酸钠在输尿管下段结石辅助排石中的作用（医疗卫生论文资料） 文1：坦索罗辛联合双氯芬酸钠在输尿管下段结石辅助排石中的作用 Evaluation of efficacy of tamsulosin and diclfenac sodium for medical expulsive treatment of lower ureteral calculi Cao Zhengguo， Sun Youwen， Zhu Yuping， Zhou Linyu， Wu Bin， Dong Xiaocheng (Department of Urology， Anhui Provincial Hospital Affiliated to Anhui Medical College， Hefei 230001， China)ABSTRACT: Objective To evaluate the efficacy of tamsulosin association with diclfenac sodium used to accelerate the expulsion of stones during the medical expulsive treatment of lower ureteral calculi to allow spontaneous passage. Methods A total of 91 coecutive patients with single radiopaque lower ureteral calculi were enrolled in the study. The stone diameter was 4～10mm and patient age was 18～57 yea. All patients were randomized in three groups. Group 1 did not receive any medical treatment as blank control group. Group 2 received tamsulosin /day and group 3 received tamsulosin plus diclfenac sodium (50mg， twice a day) for two weeks. No significant differences were found among the three groups concerning age， gender distribution and maximum stone diameter. Efficacy was evaluated in term of stone expulsion rate， expulsion time， pain episodes， analgesic use and advee drug reaction during a week of followup. Results The successful stone expulsion rate was % and % in the combination treatment group and tamsulosin group， which was significantly higher than % in the control group (P KEY WORDS: lower ureteral calculi; tamsulosin; diclfenac sodium; medical expulsive treatment 近年来，尿结石药物辅助治疗特别是选择性α1受体阻滞剂(坦索罗辛)对输尿管下段结石的辅助排石作用越来越受到国内外临床泌尿外科的重视[1]。而非甾体类抗炎镇痛药(双氯芬酸钠)在减轻输尿管水肿和疼痛发作风险上的效果也比较令人满意。目前国内外还少见坦索罗辛与双氯芬酸钠联合治疗输尿管下段结石的研究报道。作者做了一些随机对照研究，现将结果报告如下。 1 资料与方法 临