嗅鞘细胞移植对大鼠脊髓损伤后水通道蛋白4的影响（医疗卫生论文资料）.docVIP

嗅鞘细胞移植对大鼠脊髓损伤后水通道蛋白4的影响（医疗卫生论文资料） 文档信息 ： 文档作为关于“医学心理学”中“骨科学”的参考范文，为解决如何写好实用应用文、正确编写文案格式、内容素材摘取等相关工作提供支持。正文8085字，doc格式，可编辑。质优实惠，欢迎下载！ 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：嗅鞘细胞移植对大鼠脊髓损伤后水通道蛋白4的影响 1 1 材料与方法 3 2 结果 6 3 讨论 7 文2：超前镇痛对大鼠脊髓损伤后炎性介质的影响 8 1 材料与方法 9 2 结果 10 3 讨论 10 参考文摘引言： 11 原创性声明（模板） 13 文章致谢（模板） 13 正文 嗅鞘细胞移植对大鼠脊髓损伤后水通道蛋白4的影响（医疗卫生论文资料） 文1：嗅鞘细胞移植对大鼠脊髓损伤后水通道蛋白4的影响 Effect of Olfactory Sheath Cell Traplantation on Water Channel Aquaporin4 in Rats with Experimentally Injured Spinal Cord PENG Zhongyong1， CHEN Zhibin2， XIU Bo3， AO Qiang3， CAI Meihua2， SU Qingjie2， WANG Tan2， ZHAO Zhenqiang2 ( Second Department of Neurology the Second Peoples Hospital of Guiyang， Guiyang 550022， Guizhou， China; 2. Hainan Medical College， Haikou 570102， Hainan， China; 3. Department of Neurosurgery， The Second Affiliated Hospital of Tsinghua Univeity， Beijing 100039， China) [Abstract] Objective: To investigate effects of traplanted olfactory sheath cells (OSC) on the water channel aquaporin4 (AQP4) expression and function recovery of hind limbs in rats with experimentally injured spinal cord. Methods: One hundred and fifty Wistar rats were randomly divided into normal group (group N)， model group (group M) and OSC traplantation group (group OSC)， with 50 rats in each. Modified Allen method was used to establish spinal cord injury model in groups M and OSC. OSCs were traplanted into the traected site of spinal cord in group OSC， while DF12 solution was given into that of group M after the spinal cord injury model was made successfully. On the 1st， 3rd， 7th， 14th， 21st， and 28th days after the injury， the hind limb function of rats were estimated with system of BBB locomotion score， and the AQP4 expression in spinal cord tissue was determined by immunohistochemistry technique and quantity analyzed with image : From day 3 to day 28， the BBB locomotion scores of group OSC was higher than those of group M (P [Key words] spinal cord injuries; cell tra