乳腔镜下常规腋窝淋巴结清扫术治疗乳腺癌的临床效果分析.docxVIP

乳腔镜下常规腋窝淋巴结清扫术治疗乳腺癌的临床效果分析 乳腔镜下、常规腋窝淋巴结清扫术治疗乳腺癌的临床效果分析 　　【摘要】目的：比较乳腔镜下、常规腋窝淋巴结清扫术治疗乳腺癌的临床效果。方法：选取2017年 　　1月-2018年12月本科室收治的65例女性乳腺癌患者，按照治疗方法不同将患者分为对照组（常规腋窝淋巴结清扫术，32例）与观察组（乳腔镜下腋窝淋巴结清扫，33例）。比较两组患者的手术相关指标，随访6个月后，比较两组患者的上肢功能、乳房美观度、血清基质金属蛋白酶-9（mmp-9）、癌胚抗原（cea）水平及术后并發症发生情况。结果：观察组患者手术时间、术中出血量、术后引流量、住院时间均优于对照组（p0.05）;随访6个月后，观察组患者上肢内收、外展、内旋、外旋角度均大于对照组（p0.05）;观察组患者乳房美观度优于对照组（p0.05）;随访6个月后，观察组患者血清mmp-9、cea水平和术后并发症发生率均低于对照组（p0.05）。结论：乳腔镜下腋窝淋巴结清扫术可降低乳腺癌患者术中创伤，改善上肢功能，降低血清肿瘤标记物水平及术后并发症的发生。 　　【关键词】乳腔镜腋窝淋巴结清扫乳腺癌上肢功能 　　[abstract]objective：tocomparetheclinicaleffectofroutineaxillarylymphnodedissectionundermammaryendoscopeinthetreatmentofbreastcancer.method：atotalof65femalebreastcancerpatientsadmittedtoourdepartmentfromjanuary2017todecember2018wereselected，theyweredividedintocontrolgroup（conventionalaxillarylymphnodedissection，32cases）andobservationgroup（mastoscopicaxillarylymphnodedissection，33cases）accordingtodifferenttreatmentmethods.theoperation-relatedindicatorswerecomparedbetweenthetwogroups.follow-upfor6months，upperlimbfunction，breastaesthetics，serumlevelsofmatrixmetalloproteinase-9（mmp-9），carcinoembryonicantigen（cea）andpostoperativecomplicationswerecomparedbetweenthetwogroups.result：theoperationtime，intraoperativebleedingvolume，postoperativedrainagevolumeandhospitalizationtimeofpatientsintheobservationgroupwerebetterthanthoseinthecontrolgroup（p0.05）.after6monthsoffollow-up，theanglesofadduction，abduction，internalrotationandexternalrotationofupperlimbsintheobservationgroupwerelargerthanthoseinthecontrolgroup（p0.05）.after6monthsoffollow-up，thebeautyofbreastintheobservationgroupwasbetterthanthatinthecontrolgroup（p0.05）.after6monthsoffollow-up，theserumlevelsofmmp-9，ceaandtheincidenceofcomplicationsintheobservationgroupwerelowerthanthoseinthecontrolgroup（p0.05）.conclusion：mastoscopicaxillarylymphnodedissectioncanreducethetrauma，improvethefunctionofupperlimbs，andreducethelevelofserumtumormarkersandtheoccurrenceofpostoperativecomplicationsinpatientswithbreastcancer[k