瑞芬太尼微泵维持下拔除气管导管（临床医学范文）.docVIP

瑞芬太尼微泵维持下拔除气管导管（临床医学范文） 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：瑞芬太尼微泵维持下拔除气管导管 1 1 资料与方法 3 文2：瑞芬太尼微泵维持下拔除气管导管 4 1 资料与方法 5 2 结果 7 3 讨论 7 4 结论 8 参考文摘引言： 9 原创性声明（模板） 10 文章致谢（模板） 10 正文 瑞芬太尼微泵维持下拔除气管导管（临床医学范文） 文1：瑞芬太尼微泵维持下拔除气管导管 【Abstract】 Objective To study the effects of extubation associated with Remifentanil on cardiovascular respoes and wake quality in patients in general anesthesia recovery period. Methods Eighty-nine ASA Ⅰ～Ⅱgrade patients were randomly divided into three groups. They received same general anesthesia induction and same maintenance way of anesthesia. They stopped inhalation different oxygen-ether at the same time of surgery. After fifteen minutes, patients in the Remifentanil group (R group, n=30) were given 0.05～0.1μg/(kg·h) intravenous micro-pump, and patients in the Propofol group (P group, n=30) were maintained 2mg/(kg·h) intravenous micro-pump. The intravenous micro-pump of both groups was suspended after extubation. The patients in the control group (C group, n=29) immediately stopped using Remifentanil and Propofol after the surgery. After treatment, all patients in three groups had an extubation surgery. Results There was not significant difference in SBP, DBP, MAP and HR before and after extubation in R group (P0.05) and none of R group occurred choking and uncocious restlessness in anesthesia recovery period. While, SBP, DBP, MAP and HR were all increased in both P group (P0.05) and C group (P0.01). Conclusion Extubation with low-dose Remifentanil through intravenous micro-pump is not only effective in preventing cardiovascular respoes, but also can make the whole process of recovery from anesthesia fast, safety, comfort and smooth. 【Key words】 Remifentanil; extubation; cardiovascular respoes 全麻围拔管期中发生心血管反应的潜在危险已越来越受到人们的关注。引起心血管反应的主要因素是麻醉减浅后气管黏膜的刺激使交感肾上腺髓质系统的活性增加，血浆儿茶酚胺大量释放所致。近年来曾有多种方法在不同程度上减轻了此不良反应。鉴于瑞芬太尼具有起效快、苏醒快、镇痛作用强、半衰期短，其t1/2CS和t1/2ke0最短[1]的特点，本研究皆在手术结束时继以小剂量瑞芬太尼静脉泵注下拔除气管导管的临床应用价值，并与丙泊酚维持下拔除气管导管进行比较。 1