Cathepsin-L-IN-2-Z-Phe-Phe-FMK-DataSheet-生命科学试剂-MedChemExpress.pdf

Hotline: 400-820-3792 Inhibitors • Screening Libraries • Proteins www.MedChemE Cathepsin L-IN-2 Cat. No.: HY-115733 CAS No.: 108005-94-3 Synonyms: Z-Phe-Phe-FMK 分⼦式: C₂₇H₂₇FN₂O₄ 分⼦量: 462.51 作⽤靶点: Cathepsin 作⽤通路: Metabolic Enzyme/Protease 储存⽅式: Please store the product under the recommended conditions in the Certificate of Analysis. BIOLOGICAL ACTIVITY ⽣物活性 Cathepsin L-IN-2 (Z-Phe-Phe-FMK) 是⼀种有效且不可逆的组织蛋⽩酶 L (cathepsin L) 和组织蛋⽩酶 B (cathepsin B) 抑制剂。 REFERENCES [1]. Jonathan Frew, et al. Premature termination codon readthrough upregulates progranulin expression and improves lysosomal function in preclinical models of GRN deficiency. Mol Neurodegener. 2020 Mar 16;15(1):21. [2]. Kirsi Ravanko, et al. Cysteine cathepsins are central contributors of invasion by cultured adenosylmethionine decarboxylase- transformed rodent fibroblasts. Cancer Res. 2004 Dec 15;64(24):8831-8. McePdfHeight Caution: Product has not been fully validated for medical applications. For research use only. Tel: 400-820-3792; 021 Fax: 021 E-mai