免疫学发展史.pptxVIP

免疫学发展史第1页/共25页 2Stages of ImmunologyDescriptive early periodEarly attempts at vaccination: SmallpoxEarly experiments: Bacteria cause diseaseHumoral v. cellular immunitySelective v. instructive theories of I.R.The molecular revolution ? present第2页/共25页 3Descriptive Early PeriodPlagues pandemics, esp. bubonic plague (Pasteurella pestis) smallpox.Causes of disease unknown until 19th C. Thought to be caused by poisons = “virus” (latin). Thucydides (5thC. B.C.): people who recovered - immune第3页/共25页 4Early Attempts at ImmunisationMithradates VI (Anatolian King) took increasing daily doses of poi