肺癌（英文版）详细版课件.pptxVIP

Lung CancerBronchial carcinoma Advanced Lung Cancer： more than 80%Bronchial carcinoma Early stage Lung Cancer : less than 20%Why? PatientBronchial carcinoma DoctorSociety/government EpidemiologyBronchial carcinoma EpidemiologyBronchial carcinomaNo 1：Lung cancerIncidence/Mortality EtiologyBronchial carcinoma The cause is not yet clear, but agree that the incidence of lung cancer is related to the following factor : Bronchial carcinoma 1、smoking? Smoking index more than 400 Danger !! Bronchial carcinomaMale 85% Female 47% Lung cancer !! 2、air pollution Bronchial carcinoma 2、air pollution Bronchial carcinoma 2、air pollution Bronchial carcinoma ? 3、occupational exposure? ? Asbestos, ? Arsenic , Uranium , Tin Bronchial carcinoma ? 4、 Driver gene? EGFR ALK Ras Cmet ROS-1 Bronchial carcinoma PathologyBronchial carcinoma General classification (1). Central Lung Cancer? (2). Peripheral Lung Cancer?Bronchial carcinoma Histologic Classifcation: (1) Small Cell Lung Cancer (2)Non-Small Cell Lung CancerBronchial carcinoma Non-Small Cell Lung Cancer: (1) Adenocarcinoma: 35-40% (2) Squamous Cell Carcinoma:30-35% (3) Large Cell Carcinoma:10% (4) Adenosquamous Cell CarcinomaBronchial carcinoma (5) Small cell lung cancer: a. Account for approximately 15% b. Often located in proximal segmental bronchi. c. High malignancy, easy to distant spread d. Poor prognosisBronchial carcinoma Clinical manifestationBronchial carcinoma The signs and symptoms of lung cancer depend on the site ,size, the extent of invasion and metastasesBronchial carcinoma 1. When small tumor/ peripheral zoneNo symptomsBronchial carcinoma 2. When larger tumor/central zonemany symptomsBronchial carcinoma 3. When invasion/metastasesBronchial carcinoma 1.Problems caused by the tumor itself ?Cough--Most common, the bronchus involved by tumor