BD-1047-生命科学试剂-MCE.pdf

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BD-1047

Cat.No.:HY-16996

CASNo.:138356-20-4

分⼦式:C₁₃H₂₀Cl₂N₂

分⼦量:275.22

作⽤靶点:SigmaReceptor

作⽤通路:NeuronalSignaling

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性BD-1047是sigmareceptors的选择性功能性拮抗剂。BD-1047可减轻Apomorphine(HY-12723)引起的攀爬

⾏为和Phencyclidine引起的头部抽搐[1]。

客户使⽤本产品发表的科研⽂献

•CellRep.2023Jan31;42(1):112011.

•MolMed.2022Aug3;28(1):87.

•NeuralRegenRes.2024Apr3.

•IntImmunopharmacol.2023Dec22:127:111382.

•IntImmunopharmacol.2023Feb22;117:109907.

Seemorecustomervalidationsonwww.MedChemE

REFERENCES

[1].SkuzaG,etal.EffectofBD1047,asigma1receptorantagonist,intheanimalmodelspredictiveofantipsychoticactivity.Pharmacol

Rep.2006Sep-Oct;58(5):626-35.

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Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

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