2025 ACP临床指南：门诊急性发作性偏头痛的药物治疗.pdfVIP

CLINICALGUIDELINE

PharmacologicTreatmentsofAcuteEpisodicMigraineHeadachein

OutpatientSettings:AClinicalGuidelineFromtheAmerican

CollegeofPhysicians

AmirQaseem,MD,PhD,MHA;JeffreyA.Tice,MD;ItziarEtxeandia-Ikobaltzeta,PharmD,PhD;TimothyJ.Wilt,MD,MPH;

CurtisS.Harrod,PhD,MPH;ThomasG.Cooney,MD;andCarolynJ.Crandall,MD,MS;fortheClinicalGuidelines

CommitteeoftheAmericanCollegeofPhysicians*

Description:TheAmericanCollegeofPhysicians(ACP)AudienceandPopulation:Theaudienceforthisclinical

developedthisguidelinebasedonthebestavailableguidelineisphysiciansandotherclinicians.Thepopu-

evidenceonthecomparativebenefitsandharmslationisadultswithacuteepisodicmigraineheadache

ofpharmacologictreatmentsofacuteepisodicmi-(definedas1to14headachedayspermonth)man-

graineheadache,patients’valuesandpreferences,agedinoutpatientsettings.

andeconomicevidenceaboutthesepharmacologic

treatments.Recommendation1:ACPrecommendsthatclinicians

addatriptantoanonsteroidalanti-inflammatorydrug

Methods:Thisguidelineisbasedonasystematictotreatmoderatetosevereacuteepisodicmigraine

reviewandnetworkmeta-analysisofthecomparative

headacheinoutpatientsettingsfornonpregnantadults

benefitsandharmsofpharmacologictreatmentsof

acuteepisodicmigraineheadaches,aswellassys-whodonotrespondadequatelytoanonsteroidalanti-

tematicreviewsofpatients’values