MCI-727-free-base-生命科学试剂-MCE.pdfVIP

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Inhibitors•ScreeningLibraries•Proteins

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MCI-727freebase

Cat.No.:HY-19106

CASNo.:132197-26-3

分⼦式:C₂₁H₂₇N₃O

分⼦量:337.46

作⽤靶点:SecretinReceptor

作⽤通路:GPCR/GProtein

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性MCI-727freebase是⼀种⼝服有效的抗溃疡剂。MCI-727freebase可升⾼⼤⿏和⽝⾎浆促胰液素浓度。MCI-

727freebase能通过促进内源性分泌素释放刺激⼤⿏胰腺外分泌,对轻度急性胰腺炎有预防和治疗效果。

MCI-727freebase可⽤于溃疡相关疾病的研究。

REFERENCES

[1].KawamuraM,etal.EffectsofMCI-727,anewanti-ulceragent,onplasmasecretinconcentrationinratsanddogsandpancreatic

exocrinesecretioninrats.JpnJPharmacol.1991Aug;56(4):513-22.

[2].TachibanaI,etal.EffectsofMCI-727onpancreaticexocrinesecretionandacutepancreatitisintwoexperimentalratmodels.Pancreas.

1996Mar;12(2):165-72.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

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