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M2698(Standard)

Cat.No.:HY-100501R

CASNo.:1379545-95-5

分⼦式:C₂₁H₁₉ClF₃N₅O

分⼦量:449.86

作⽤靶点:RibosomalS6Kinase(RSK);ReferenceStandards;Akt

作⽤通路:MAPK/ERKPathway;Others;PI3K/Akt/mTOR

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性M2698(Standard)是M2698(HY-100501)的分析标准品。本产品⽤于研究及分析应⽤。M2698

(MSC2363318A)是⼀种具有⼝服活性，ATP竞争的，选择性的p70S6K和Akt双重抑制剂，对于

p70S6K，Akt1和Akt3的IC50均为1nM。M2698可以透过⾎脑屏障，具有抗癌活性。

REFERENCES

[1].MachlA,etal.M2698isapotentdual-inhibitorofp70S6KandAktthataffectstumorgrowthinmousemodelsofcancerandcrossesthe

blood-brainbarrier.AmJCancerRes.2016Mar15;6(4):806-18.

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