Nudifloramide-13C-d3-2PY-sup-13-sup-C-d-sub-3-sub-生命科学试剂-MCE.pdfVIP

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Nudifloramide-13C,d3

Cat.No.:HY-113432S2

Synonyms:2PY-13C,d3

分⼦式:C₆₁₃CH₅D₃N₂O₂

分⼦量:156.16

作⽤靶点:Isotope-LabeledCompounds;EndogenousMetabolite;PARP

作⽤通路:Others;MetabolicEnzyme/Protease;CellCycle/DNADamage;

Epigenetics

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性Nudifloramide-13C,d3(2PY-13C,d3)是13C和氘代标记的Nudifloramide(HY-113432)。Nudifloramide

(2PY)是烟酰胺-腺嘌呤⼆核苷酸(NAD)降解的最终产物之⼀。Nudifloramide在体外可显著抑制PARP-1活性

。

体外研究Stableheavyisotopesofhydrogen,carbon,andotherelementshavebeenincorporatedintodrugmolecules,

largelyastracersforquantitationduringthedrugdevelopmentprocess.Deuterationhasgainedattention

becauseofitspotentialtoaffectthepharmacokineticandmetabolicprofilesofdrugs.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.