N-N-Pentane-1-5-diyl-bis-2-chloroacetamide-生命科学试剂-MCE.pdfVIP

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N,N-(Pentane-1,5-diyl)bis(2-chloroacetamide)

Cat.No.:HY-W175189

CASNo.:33619-33-9

分⼦式:C₉H₁₆Cl₂N₂O₂

分⼦量:255.14

作⽤靶点:PROTACLinkers

作⽤通路:PROTAC

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性N,N-(Pentane-1,5-diyl)bis(2-chloroacetamide)是⼀种PROTAClinker，可⽤于合成PROTAC分⼦。

体外研究PROTACscontaintwodifferentligandsconnectedbyalinker;oneisaligandforanE746ubiquitinligase

andtheotherisforthetargetprotein.PROTACsexploittheintracellularubiquitin-proteasomesystemto

selectivelydegradetargetproteins.

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Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

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