N-N-Ethane-1-2-diyl-bis-2-bromoacetamide-生命科学试剂-MCE.pdfVIP

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Inhibitors•ScreeningLibraries•Proteins

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N,N-(Ethane-1,2-diyl)bis(2-bromoacetamide)

Cat.No.:HY-W614943

CASNo.:4960-81-0

分⼦式:C₆H₁₀Br₂N₂O₂

分⼦量:301.97

作⽤靶点:PROTACLinkers

作⽤通路:PROTAC

储存⽅式:Powder-20°C3years

4°C2years

Insolvent-80°C6months

-20°C1month

BIOLOGICALACTIVITY

⽣物活性N,N-(Ethane-1,2-diyl)bis(2-bromoacetamide)是⼀种PROTAClinker，可⽤于合成PROTAC分⼦。

体外研究PROTACscontaintwodifferentligandsconnectedbyalinker;oneisaligandforanE745ubiquitinligase

andtheotherisforthetargetprotein.PROTACsexploittheintracellularubiquitin-proteasomesystemto

selectivelydegradetargetproteins.

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Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

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