N-N-Dimethyldodecylamine-生命科学试剂-MCE.pdfVIP

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N,N-Dimethyldodecylamine

Cat.No.:HY-W235067

CASNo.:112-18-5

分⼦式:C₁₄H₃₁N

分⼦量:213.4

作⽤靶点:Dynamin

作⽤通路:Cytoskeleton

储存⽅式:4°C,protectfromlight

*Insolvent:-80°C,6months;-20°C,1month(protectfrom

light)

BIOLOGICALACTIVITY

⽣物活性N,N-Dimethyldodecylamine是⼀种动⼒蛋⽩I(dynaminI)抑制剂。N,N-Dimethyldodecylamine对动⼒蛋⽩I

的GTP酶的IC50为14.79μM。N,N-Dimethyldodecylamine可⽤于阿尔茨海默病、亨廷顿病等与内吞作⽤

缺陷相关疾病的研究。

REFERENCES

[1].HillTA,etal.LongchainaminesandlongchainammoniumsaltsasnovelinhibitorsofdynaminGTPaseactivity.BioorgMedChemLett.

2004Jun21;14(12):3275-8.

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