Norbinaltorphimine-dihydrochloride-Standard-生命科学试剂-MCE.pdfVIP

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Norbinaltorphiminedihydrochloride(Standard)

Cat.No.:HY-100903R

CASNo.:113158-34-2

分⼦式:C₄₀H₄₅Cl₂N₃O₆

分⼦量:734.71

作⽤靶点:OpioidReceptor;ReferenceStandards

作⽤通路:GPCR/GProtein;NeuronalSignaling;Others

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性Norbinaltorphiminedihydrochloride(Standard)是Norbinaltorphiminedihydrochloride(HY-100903)的分

析标准品。本产品⽤于研究及分析应⽤。Norbinaltorphiminedihydrochloride是⼀种有效的和选择性的κ阿

⽚受体(κopioidreceptor)拮抗剂。

IC50Targetκopioidreceptor[1]

REFERENCES

[1].BirchPJ,etal.Norbinaltorphimine:antagonistprofileatkappaopioidreceptors.EurJPharmacol.1987Dec15;144(3):405-8.

[2].FlaxSM,etal.Effectofnorbinaltorphimineon∆⁹-tetrahydrocannabinol(THC)-inducedtasteavoidanceinadolescentandadultSprague-

Dawleyrats.Psychopharmacology(Berl).2015Sep;232(17):3193-201.

[3].JacksonKJ,etal.Effectsofthekappaopioidreceptorantagonist,norbinaltorphimine,onstressanddrug-inducedreinstatementof

nicotine-conditionedplacepref