DWI在脑部的应用PPT演示课件.pptxVIP

DiffusionweightedMRimaging

innon-infarctlesionsofthebrain

DWI在非梗塞性脑病变中的应用

Introduction

·Diffusionweightedimaging(DWI)isbasedonthesensitivityofMRtomicroscopicmobilityofwatermoleculeswithintissues.

·DWI基于MR对组织内水分子微观运动的敏感性

·DWIconsistsofaDWimageandanapparentdiffusioncoefficient(ADC)

map.

·DWimage,togetherwithqualitativeandquantitativeassessmentofthe

ADCmaphasbeenwidelyusedinthediagnosisofacutecerebral

infarction,owingtothereliabledistinctionofcytotoxicandvasogenic

edema.

·由于DWI联合定性及定量的ADC图可以鉴别细胞毒性和血管源性水肿，

已广泛地应用在急性脑梗塞的诊断

·Edemaisanon-specificreactionofbrainparenchymetodiffenernt

factors,whichcanbedifferentiatedbyDWI.

·DWI可鉴别不同因素导致的脑实质的非特异性反应--水肿

Introduction

·Cytotoxicedema-characterizedbyabnormalcellularuptakeofwaterandmyelinedema-characterizedbyintramyelinicaccumulationofvacuolated

orfreewater-havehighsignalintensityonthediffusiontrace,with

decreasedADCasaresultofisotropicallyrestrictedwaterdiffusion.

·Ontheotherhand,vasogenicedema,causedbyincreasedpermeabilityof

theblood-brainbarrier,andinterstitialedema,causedbysubependymal

waterdiffusioninacutehydrocephalushaveintermediatesignalontheDW

imagewithincreasedADC

·DWI区分水肿的性质：

细胞毒性水肿和和髓鞘性水肿——由于同向性弥散受限，弥散相呈高

信号，ADC值下降；

血管源性水肿和间质性水肿——弥散不受限，弥散相呈中等信号，

ADC值升高。

Introduction

·AlthoughDWIhasbeentriedfordifferentorgansystems,ithasbeenfounditsprimaryuseinthecentralnervoussystem.

·Themostwidelyusedclinicalapplicationisinthedetectionof

hyperacuteinfarctsandthedifferentiationofacuteorsubacute

infarctionfromchronicinfarction

·尽管DWI已经应用在不同系统的器官，但是主要应用在中枢神经系统。

·临床最广泛的应用是诊断超急性脑梗塞和鉴别急性或亚急

性脑梗塞与陈旧脑梗塞

Introduction

·RecentlyDWIhasbeenappliedtovariousothercerebral

diseases.

·现在DWI被应用在多种脑部疾病

·Inthispaper,IdemonstratedifferentDWIpatternsofnon-infarc