经络穴位与肥大细胞相关性研究进展.pdfVIP

针刺研究 　2005 年 6 月 　第 30 卷 　第 2 期 115 ☆综 　　述 ☆ 经络穴位与肥大细胞相关性研究进展 1 张 　迪 　丁光宏 　沈雪勇 　姚 　伟 　林 　俊 (复旦大学力学与工程科学系 ,上海市针灸经络研究中心 , 上海 200433 ; 1 ) 上海中医药大学针灸推拿学院 , 上海 200032 【摘 　要】　本文研究了经络穴位与肥大细胞在结构和功能上所存在的相关性 ,为探讨经穴处的物质基础及 针刺疗效的作用机理提供理论依据。文中结合了肥大细胞细胞生物学和生理学的相关资料 ,对近年研究针 刺在经穴处引起肥大细胞效应的有关文献加以回顾 ,认为肥大细胞沿经线富集 ,针刺经穴后促使其释放介质 与针刺疗效作用机理之间存在可能的相关性。 【关键词】　经络 　肥大细胞 　脱颗粒 　组织胺 　综述 ( ) 【中图分类号】R224. 1 　【文献标识码】A 　【文章编号】1000 - 0607 2005 02 - 0115 - 05 Study on the Correlation bet ween Meridian Acupoints and Mast Cells ZHAN G Di , 　DIN G Guanghong , 　SHEN Xueyong1 , 　YAO Wei , 　L IN J un ( Dept . of Mechanics and En gineerin g Science , S hanghai Research Cent re of A cumoxibustion and Meridians , Fudan U niversity , S hang hai , 2 00433 ; 1A cumoxibustion College , S hanghai U niversity of TCM , S hanghai , 2 00032) 【ABSTRACT】　The present paper reviews development of researches on the correlation between mast cells (MCs) and meridianacupoints from 1 ) distribution and morpholo gical characters of MCs , 2) effects of acupuncture on the de granulation , rejuvenation , number , and mediator release of MCs , 3 ) the relationship between the propa gation of the stimulationinduced sensation along the meridian ( PSISM) and MCs : a) cas cade reactions of cytokines of MCs and their biolo gical effects , b) release of mediators of MCs and PSISM. Meridiancollateral system and MCs have a clo se correlation in both the function and structure. MCs in the connective tissues are called as “the migration brain”and vary in functions. Whereas the regulati