新疆地区四肢长骨骨巨细胞瘤的外科治疗.pdfVIP

1244 中国肿瘤临床2013年第40卷第20期 Chin J Clin Oncol 2013,Vol.40,No.20 新疆地区四肢长骨骨巨细胞瘤的外科治疗* 陈江涛 周义军 田 征 艾克拜尔·尤努斯 徐磊磊 朱晓萌 宋兴华 摘要 目的：回顾性分析长骨骨巨细胞瘤不同手术方法的临床疗效。方法：回顾2007年1月至2012年6月收治四肢长骨骨 巨细胞瘤37例，男性20例，女性17例；平均年龄为31.6（20～56）岁。分析假体置换手术和非假体置换手术对术后的复发、肢体功 能，综合评定其影响；不同民族之间发病率，复发率的分析；上下肢的发病率，复发率的分析。结果：本研究病例好发年龄为 20～50岁，维吾尔族发病率较高，民族之间复发率差异无统计学意义（P0.05）。结论：骨巨细胞瘤好发年龄为20～50岁，维吾尔 族发病率较汉族及其他民族高。下肢发病率及复发率均要高于上肢。切除后植骨或骨水泥填充、植骨内固定、瘤段切除人工关 节置换均是骨巨细胞瘤的可靠治疗方法。 关键词 骨巨细胞瘤 切除术 关节成形术 置换 doi:10.3969/j.issn.1000-8179 Surgical treatment of giant-cell tumor of long extremity bones Jiangtao CHEN, Yijun ZHOU, Zheng TIAN, Aikebaier YOUNUSI, Leilei XU, Xiaomeng ZHU, Xinghua SONG Correspondence to: Xinghua SONG; E-mail: songxinghua19@163.com Department of Bone Tumors, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, China This work was supported by the National Natural Science Foundation of China (No. Abstract Objective: To analyze the clinical effect of different surgical methods on giant-cell tumor of bone (GCTB). Methods: Between January 2007 and June 2012, 37 patients receiving treatment for GCTB were enrolled in this study. These patients included 20 males and 17 females whose ages ranged from 20 to 56 (average=31.6). The prosthesis replacement and nonprosthetic replacement op- eration on the postoperative recurrence, limb function, comprehensive evaluation of the curative effect, as well as morbidity and recur- rence rate among different nations and in the upper and lower limbs of GCTB patients were analyzed. Results: The predilection age of the cases ranged from 20 to 50 years old. The incidence was higher in the Uighur population of Xinjiang, China. However, the recur- rence rate in ethnic difference was not statistically significant (P 0.05). Conclusion: The predilection age of GCTB cases was 20 ～50 years old, with higher