复方天麻蜜环菌片治疗椎基底动脉供血不足65例疗效观察.pdfVIP

维普资讯 · 60 · ChineseJoumM ofClinicalHeahhcare，February2007，Vol10No．1 基底动脉 ·论著 · 复方天麻蜜环菌片治疗椎 供血不足65例疗效观察 王新强，尹继君，孟范文，彭玉华，林峰 (山东聊城市第二人民医院神经内科，252601) 【摘要] 目的 探讨复方天麻蜜环菌片治疗椎基底动脉供血不足(VBI)的临床疗效。方法 将椎基底 动脉供血不足的住院和门诊患者共 130例，随机分为治疗组(65例)和对照组(65例)，两组均使用复方丹参 注射液为基础治疗，疗程21d；治疗组加用复方天麻蜜环菌片，疗程21d。疗程结束后，评定疗效及复查彩色 多普勒超声 (TCD)。结果 治疗组总有效率为93．8％；对照组总有效率为81．5％，差异有统计学意义 (P 0．05)。治疗组治疗前后比较，血流动力学和椎基底动脉平均血流速度等指标的变化差异均有统计学意义(P 0．05或P0．01)。结论 复方天麻蜜环菌片能降低全血黏度和血小板聚集，改善脑供血，为治疗椎基底动 脉供血不足的安全有效药物。 【关键词] 椎底动脉供血不足；血液流变学；中草药 【中图分类号]R543．5 【文献标识码]A 【文章编号]1672-6790(2007)0143060-03 65casesofclinicalobservation ofapplyingcompoundarmillariamellea tabletsin vertebro-basilar WANG Xinqiang，YIN．，n，MENGFanwen，PENGYuhua，LIN 凡g(DepartmentofNeurology，SecondPeoplesHospitalofLi- aochengCity，Shandong252601，China) [Abstract] Objective Toexploretheclinicaleffectofcompoundarmillariamelleatabletsonthetreatmentof ver-tebrobasilarinsufficiency(VBI)．Methods 130inpatientsandoutpatientswithvertigocausedbyVB1wereran- domlydividedintotwogroups．Bothgroupsweretreatedwithcompoundradixsalviaemihiorrhizaeinjectionasbasic curefor21days，nadthetreatmentgroup(65cases)Was addedtoorallycompoundarmillariamelleatbaletsofr 21days．Thecurativeeffectswereevaluatednadcolortrnascranial dopplersonography(TCD)Was repofformde． Results Th etotal effectiverateofthetreatmentgroupWas 93．8％ ．whilethethatofhtecontrolgroupWas 81．5％ ． ThecurativeeffectoftreatmentgroupWassignificnatthna thatofthecontrolgroup(P0．05)．Toevaluatetheeffect ofthetreatmentgroupbeforethna afterthetreatment，thedifferencesintargetssuchas cerebralbloodhemocynamics nadtheaveragevelocityofverbralnadbasilararterias wereremarkable(PO．05orPO．01)。Conclusion Corn- poundarmillariamelleatabletsCna reducewholebloodviscosityandnati-plateletaggregationimprovebrain~blood supply。SoitissecurenadeffectivetotreatVBI。