【环境工程专业】【毕业论文+开题报告+文献综述】三聚氰胺分子印迹聚合物的制备微球及其在固相萃取中的应用.doc

（20 届） 毕业设计 三聚氰胺分子印迹聚合物的制备微球及其在固相萃取中的应用 摘 要 三聚氰胺广泛用于塑料、涂料、粘合剂和食品包装材料的生产，同时三聚氰胺也是畜牧业和农作物常用杀虫剂环丙氨嗪的代谢产物，近年来在地表水和土壤中分别检出了三聚氰胺的残留。三聚氰胺已波及整个食物链，对生态环境和饮用水安全构成潜在的威胁，因此监测环境中的三聚氰胺有重要意义。分子印迹技术可使聚合物结构中形成对膜板分子具有特殊性的结合位点。在由自由基引发的聚合过程中，模板分子和功能单体形成的主客体配合物进入聚合物的结构。洗去模板分子后，聚合物中留下对模板分子具有特异性结合能力的位点。2-丙烯酰胺-2-甲基丙磺酸为功能单体，乙二醇二甲基丙烯酸酯为交联剂，采用水溶液悬浮聚合法合成分子印迹聚合物微球。并用扫描电镜表征。通过静态平衡结合实验研究该聚合物的结合能力和选择性能，并将所得的MIP用于自制固相萃取柱的固定相，研究其从加标三聚氰胺的奶制品中萃取三聚氰胺的性能； 关键词：分子印迹技术；分子印迹聚合物；； The Microspheres Pruduction of Molecularly Imprinted Polymer Melamine and Its Application in Solid Phase Extraction Abstract Melamine is widely used in plastics, coatings, adhesives and food packaging materials production, while melamine is the metabolite of insecticide cyromazine which is commonly used in livestock and crops.In recent years, melamine residues were detected in surface water and soil respectively. Melamine has affected the entire food chain, and it poses a potential threat to drinking water safety and the ecological environment, so monitoring the melamine in the environment is so important . Molecular imprinting technology allows the formation of binding sites in the polymer structure which is special to the film board molecular. In the polymerization process caused by free fadical group, the host-guest complex formed from the template molecule and the functional monomers goes into the polymer structure. After the template molecule is washed away , the sites which has a specific binding capacity to the polymer molecules in the polymer stayed. This experiment uses melamine as the template molecule, methacrylic acid and 2 - acrylamide -2-- methyl propane sulfonic acid as functional monomer, ethylene glycol dimethacrylate as crosslinker,and uses aqueous suspension polymerization to sythesize molecularly Imprinted polymer microspheres and take the method of scanning electron microscope. Through equilibrium binding experiments, we investigate the binding capacity and the choosing properties of the polymer, and apply