高频超声对脑梗死患者颈股动脉解剖结构变化的研究.DOCVIP

临床医学论文-高频超声对脑梗死患者颈股动脉解剖结构变化的研究 ????????????????? 作者：王凤玲，何光彬，刘荣桂 【关键词】? 彩色多普勒；颈动脉；股动脉；　　［摘要］ 目的：应用高频超声观察脑梗死患者颈动脉(CA)、股动脉(FA)解剖及结构变化、内中膜厚度(IMT)、斑块数目、回声，以探讨脑梗死与CA、FA硬化的相互关系。方法：对50例脑梗死患者和40例健康老年人CA、FA行高频超声检查，观察颈、股动脉内中膜有无增厚、有无斑块、斑块数目和回声情况。结果：脑梗死组CA　IMT为(0.70±0.13)mm，明显大于对照组(0.56±0.11)mm，(P0.05)；FA IMT(0.72±0.14)mm，明显大于对照组(0.59±0.09)mm，(P0.05)；脑梗死组CA、FA斑块发生率高于对照组(P0.05)。结论：高频超声是无创诊断早期动脉硬化(AS)的简便有效方法，应用外周大血管的解剖结构变化可间接评价全身动脉硬化程度。为临床预防脑血管疾病提供帮助。 　　［关键词］ 彩色多普勒；颈动脉；股动脉；内中膜厚度； 　　HighFrequency Ultrasound Assessment of Carotid Femoral Artery Anatomic Structure in Patients with Cerebral Infarction 　　Abstract: Objective To study the changes(including intima media thickness，echo and numbers of plaque) of the anatomic structureof carotid artery(CA)、femoral artery(FA) in patients to assessment the relation between sclerosis of CA and FA and erebral infarction utilizing highfrequency ultrasound．Methods CA and FA in fifty patients and forty healthy adults were examined with bighfrequency ultrasound．We measured intimamedia thickness(IMT)and observedthe echo of the intimamedia，the echo and number of plaque． Results IMT measurements of the CA(0.70±0.13) mm and FA(0.72±0.14) mm were greater in persons with cerebral infarction than those without CA(0.56±0.11) mm，FA(0.59±0.09)mmP0.05)．The plaque of CA and FA in the cerebral infarction group increased than the control(P0.05)． Conclusions HighFrequency ultrasound could effectively and noninvasively measured arteriosclerosis．With measuring peripheral vessels changes indirectly ssess sclerosis of blood vessels of the whole body，according to which make clinical diagnosis． 　　Key words：Color doppler; Carotid artery; Femoral artery; Intimamedia thickness 　　动脉粥样硬化属全身性病变，外周动脉与脑动脉之间存在着相似的病理、生理基础，通过观察外周大血管解剖结构变化特征作为窗口，可间接评价全身动脉硬化及其程度，特别是为脑动脉硬化的发生和发展提供无创的参照，还可为颈动脉粥样硬化的药物和外科手术治疗起到重要的指导作用，本研究应用高频超声通过观察脑梗死患者颈动脉(CA)、股动脉(FA)的内中膜厚度、斑块形状，评价二者之间的相关性，以期作为评价脑动脉硬化的预防、诊断及预后的方法。 　　1　对象和方法 　　1．1　对象　脑梗死患者为西京医院住院患者50例(男28例，女22例)，年龄46岁～70岁，平均年龄(59±9)岁，经CT或MRI检查确诊为脑梗死，对照组