2005,JBO,二氧化钛纳米粒子的大小的影响,进入角质层,对,紫外A和紫外B,皮肤的防晒特性(APP,AVP,等).pdfVIP

Journal of Biomedical Optics 106, 064037 November/December 2005 Effect of size of TiO2 nanoparticles embedded into stratum corneum on ultraviolet-A and ultraviolet-B sun-blocking properties of the skin Alexey P. Popov Abstract. Recently there has been a strong demand to protect human M. V. Lomonosov Moscow State University skin against negative effects of the UV solar light. This problem is Physics Department and International Laser Center interesting due to the increased frequency of human diseases caused Vorobiovy Gory Moscow, 119992 Russia by such radiation. We aim to evaluate how the optical properties of and the horny layer of skin can be effectively changed by imbedding TiO2 University of Oulu and Infotech Oulu fine particles to achieve the maximal attenuation of the UV solar ra- Optoelectronics and Measurement Techniques diation. In-depth distribution of TiO2 particles embedded into the skin Laboratory by multiple administration of sunscreens is determined experimentally 90014 Finland E-mail: dwelle@rambler.ru using the tape-stripping technique. A computer code implementing the Monte Carlo method is developed to simulate photon migration within the 20-m-thick horny layer filled with nanosized