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ActaEntomologica Sinica, June 2006, 49 ( 3) : 497- 503 ISSN 0454-6296
1, 2 2* 1 1
王 敦 , 唐振华 , 尚金燕, 张传溪
( 1, 310029; 2 , 200032)
: ( acetylc olinesterase, AC E, EC 3117)
, 10 AC E
, AC E , AC E AC E
, AC E AC E
AC E
: ; ; ; ;
: Q966 : A : 0454-6296 (2006) 03-0497-07
Advances in the studies of acetylcholinesterase genes from insects
1, 2 2* 1 1
WANG Dun , TANG Z en-Hua , SHANG Jin-Yan , ZHANG C uan-Xi ( 1 Institute of Applied
Entomology, Z ejiang University, Hangz ou 310029, C ina; 2S ang ai Institute of Plant P ysiology and
Ecology, C inese Academy of Sciences, S ang ai 200032, C ina)
Abstract: Recent advances in t e studies of acetylc olinesterase ( AC E, EC 3117) genes from insects
were reviewed. T e gene structure, including ten extrons of insect AC E gene ( ace) , was discussed. All t e
ace genes reported from insects were summed up, and t e p ylogenetic tree was constructed based on t e
reported complete sequences of ace genes from insects. T e ace structure c aracteristics, t e functional sites
of ace genes, t e effect of ace mutation ( s) on insecticide resistance and t eir relations ips were also
discussed. Finally, t e problems and prospects in t e studies of insect ace were analyzed.
Key words: Acetylc olinesterase; acetylc olinesterase genes; molecular evolution; mutation; resistance
Dale ( 1914) , Fournier ( 1989)
( acetylc olinesterase, AC E, EC3117) Drosophila melanogaster AC E
, 80 , AC E
, ; Taylor Radie ( 1994) AC E
, Tropedo calfi ornia
(AC ) AC E , ( 1996)
(OP) ( CB) , ( 2003) AC E
AC E , ; ( 2005) AC E
( Ser) AC E
AC E, AC E ( , GenBank
) ace cDNA ;
AC E ,
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