周玉蓓丹参酮注射液治疗例冠心病心绞痛的临床应用体会.docVIP

丹参酮注射液治疗26例冠心病心绞痛的临床应用体会 周玉蓓 [摘要] 目的：探讨丹参酮治疗冠心病心绞痛的作用机理和评价其近、远期疗效。方法：选择我院2010年3月-12月52例冠心病心绞痛患者为研究对象，按照就医先后的顺序，随机分为两组，观察组使用丹参酮40mg qd；对照组使用硝酸甘油5mg＋脉络宁40ml qd，两组疗程为2周。观察两组治疗前、后的血脂、心电图、血流变的改善情况。结果：对照组显效率50.00%，观察组显效率53.85%；出院后4W内心绞痛平均复发次数，观察组为2.3次，对照组为6.5次；观察组血脂、血流变的改善状况明显优于对照组。结论：丹参酮用于冠心病心绞痛其疗效迅速且确切，具有较好的远期效果，值得在基层医院推广使用。 [关键词]：心绞痛；丹参酮注射液；作用机理 Clinical application of tanshinone injection in the treatment of 26 cases of angina pectoris of coronary heart disease Zhou Yu-bei [Abstract] Objective: To investigate the mechanism and evaluation of Tanshinone in treatment of angina pectoris of coronary heart disease and its close, long-term effect. Methods: in our hospital in 2010 March -12 months in 52 cases of angina pectoris of coronary heart disease patients as the research object, according to medical order, were randomly divided into two groups, the observation group use of tanshinone 40mg QD; the control group using nitroglycerin 5mg + Mailuoning 40ml QD, the two groups were treated for 2 weeks. The two groups were observed before and after treatment, blood lipid, electrocardiogram, blood rheology. Results: in the control group was 50%, the observation group markedly effective rate of 53.85%; the number of times 4W angina recurrence after discharge, the observation group was 2.3, control group 6.5; observation group is obviously better than that of improving the condition of blood lipid, blood rheology control group. Conclusion: tanshinone for coronary heart disease and angina pectoris curative effect quickly and exactly, has long-term effect is good, worthy of promotion in the primary hospital use. [ keyword ]: angina pectoris; Salvia miltiorrhiza injection; mechanism of action 随着现代医学研究的不断深入，各种理化检查设备也在不断的更新、升级，如对冠心病心绞痛的诊断能更准确和直观，为患者的药物治疗提供一良好的平台。目前，治疗冠心病心绞痛的药物较多，其药理机制都基本一致，但各种药物作用又存在一定的差异。2010年3月-12月我院运用丹参酮注射液治疗26例冠心病心绞痛患者，取得满意的疗效，现报道如下： 1 资料与方法 1.1一般资料 本组52例均为我院2010年3月-12月住院患者，经客观理化检查均符合冠心病心绞痛诊断标准，我们按照患者就医的先后顺序随机平均分为两组（使用丹参酮注射液称观察组，使用硝酸甘油和脉络宁称对照组）。本组患者男性35例，女性1