安神饮合益聪浆对失眠患者睡眠质量及焦虑抑郁状态的影响_药学论文.docVIP

安神饮合益聪浆对失眠患者睡眠质量及焦虑抑郁状态的影响_药学论文 安神饮合益聪浆对失眠患者睡眠质量及焦虑抑郁状态的影响_药学论文 【关键词】 失眠症；,,焦虑；,,抑郁；,,血液流变学；,,安神饮；,,益聪浆 　　摘要：目的观察安神饮和益聪浆对失眠症患者睡眠质量、焦虑抑郁状态的疗效。方法将符合失眠症诊断的病例随机分为中药组和西药组，中药组服安神饮合益聪浆，西药组服舒乐安定、谷维素、维生素B1，采用PSQI，SAS，SDS量表治疗前及治疗后2，4周评定1次，治疗前后行血流变学检查，两组均4周统计疗效，停药后3个月统计复发率。结果组内治疗前后比较，两组PSQI，SAS，SDS均有显著性差异（0.001）；治疗4周后与对照组比较：PSQI，SAS，SDS均有显著性差异（0.001）；血流变学检查：组内治疗前后比较均有显著性差异（0.05），治疗4周后与对照组比较，红细胞压积、全血低切还原黏度、全血高切还原黏度、血浆黏度值、全血黏度值均有显著性差异（0.05）；中药组总有效率91.1%，西药组总有效率83.9%（0.05）；中药组复发率为20.7%，西药组复发率为43.6%(0.005)。结论安神饮合益聪浆治疗失眠症，对睡眠质量、焦虑抑郁状态优于西药组。 　　关键词：失眠症； 焦虑； 抑郁； 血液流变学； 安神饮； 益聪浆 　　The Influence of AnShen Yin combined with YiCongJiang on Sleep Quality, Anxiety/Depression Conditions of Insomnia Patients 　　Abstract:ObjectiveTo assess the clinical effect of AnShen Yin combined with YiCongJiang on sleep quality, anxiety/depression conditions of insomnia patients.MethodsInsomnia patients were randomly divided into two groups-Chinese Traditional Medicine Group (CTMG) and Western Medicine Group (WMG). Patients in CTMG were given AnShen Yin combined with YiCongJiang; and patients in the other group were given Estazolam, Oryzanol and Vitamine B1. All patients were evaluated using questionnaires including the Pittsburgh Sleep Quality Questionnaire (PSQI), self-rating anxiety and depression scale (SAS and SDS) before treatment, in the second and fourth week of the treatments. Blood hydrodynamics was also determined before and during the treatments. The efficacy of the medicine in both groups was evaluated after four-week treatments. Relapse rate was also inspected three months after stopping the treatment.ResultsComparing the results between before and after the treatment in the same group, PSQI, SAS and SDS had significant difference in each group (P＜0.001).Comparing the results of 4-week treatments between two groups, PSQI, SAS and SDS had significant difference between the groups (P＜0.001). Based on blood hydrodynamics tests, remarkable difference was found before and after the treatments in th