清热解毒法治疗流行性乙型脑炎332例临床观察.pdfVIP

清热解毒法治疗流行性乙型脑炎332例临床观察 涂晋文1 董梦久1刘志勇2 牟艳杰2 1.湖北省中医院(430061)2.湖北中医药大学(430065) [摘要]目的：观察清热解毒法治疗流行性乙型脑炎的临床疗效。方法：332例流行性乙型脑 炎，其中随机研究组163例，队列研究组169例。随机研究组患者分为西药对照组和中药治疗 组，队列研究组患者分为西药对照组和中药治疗组，分别比较2组间的临床疗效。结果：随机 研究治疗组在降温(5.12±2.20天)、平均昏迷时间(3.35±1.42天)、平均缓解抽搐时间(3.8 ±2.20天)、平均住院天数(20±2.50天)；队列研究治疗组在降温(5.50±1.30天)、平均昏迷 时间(5.84±1.03天)、平均缓解抽搐时间(2.23±1.19天)、平均住院天数(23±2.19天)均比 对照组短，且恶化和后遗症较少，治愈率高；随机研究组和队列研究组中，治疗组临床有效率 均优于对照组(p＜0.05)，并且在降低体温、缓解抽搐、意识恢复、平均住院时间均优于对照组 (p＜0.05)。结论：清热解毒法对流行性乙型脑炎有显著疗效。 [Abstract]ObjectiveRemovingheatandtoxicclinicalefficacyforthetreatmentof encephalitiswereobserved.Method332casesofencephalitis,whichrandomizedstudy groupof163cases,cohortstudyof169cases.Randomizedstudygrouppatientswere dividedintowesternmedicineinthecontrolgroupandtreatmentgroup,cohortstudy ofpatientsintothecomparisongroup,andthetreatmentgroup,respectively,compare theclinicalefficacybetweenthe2groups.ResultTherandomizedstudytreatmentgroup cooling(5.12 ± 2.20days),averagecomatime(3.35± 1.42days),averageeasethe twitchtime(3.8± 2.20days),averagedaysofhospitalizationnumber(20± 2.50days); queuestudytreatmentgroupinthecooling(5.50± 1.30days),theaverageduration ofcoma(5.84± 1.03days),theaverageeaseconvulsions(2.23± 1.19days),average hospitaldays(23± 2.19days)thanthecontrolgroupisshort,anddeteriorationand sequelaelesshighcurerate;randomizedstudygroupandcohortstudygroups, the clinicaleffectiverateoftreatmentgroupthanthecontrolgroup(p＜0.05),recovery andreducebodytemperature,relieveconvulsions,consciousness,theaveragelength ofstayarebetterthanthecontrolgroup(p＜0.05).ConclusionHaveasignificanteffect ofremovingheatandtoxicencephalitis.