盐酸戊乙奎醚对开胸手术患者呼吸循环功能的影响.pdfVIP

· 986 · 赵文晖，等 盐酸戊乙奎醚对开胸手术患者呼吸循环功能的影响 临床 麻 醉 夺 盐酸戊乙奎醚对开胸手术患者呼吸循环功能的影响 赵文晖 ，党晓东 ，景桂霞 Effectsofpenehyclidinehydrochlorideonrespiratoryandcirculatory functioninpatients undergoingthoracicsurgery ZhaoWenhui，DangXiaodong，JingGuixia DepartmentofAnesthesiology，ShaanxiProvincialTumorHospital，ShaanxiXian710061，China；DepartmentofAnesthesiology，theFirst AffiliatedHospital，MedicalSchoolofXianJiaotongUnivemity，ShaanxiXian710061，China． A【bstract】 Objective：Tocomparetheeffectsofpenehyclidinehydrochlorideandatropineonrespiratoryandcircu— latory functioninpatientswiththoracicsurgery．Methods：EightypationswithASAIorIItreatedwiththoracicsurgery wererandomlydividedintotwogroups(rgoupPandrgoupA)with40patientsineachrgoups．GroupPreceivedpene— hyclidinehydrochloride(rgoupP0．Olmg／kg)groupAwasadministeredwithatropine(rgoupA0．Oimg／kg)．Mean artery pressureandheartratewererecorded，thearterialbloodsamplesweretakenandPpeak，Pplat，Compl，Pawwere recordedatthetimepointofbeforeoperation(T1)，30min(T2)，60min(T3)afterone—lungventilation，15minafter doublelungventilation(T4)．Results：TheCompl，Ppeak，Pplat，ComplandPawingroupPwassignificantlylower thaninrgoupAatT2，T3，T4(P0．05)，SaO2inrgoupPwassignificantlyhigherthaninrgoupAatT2，T3，T4(P 0．05)．HeartratewaslowerinrgoupPthangroupAatT2andT3(P0．05)．Conclusion：Comparedwithatropine， penehyclidinehydrochloridecaneffectivelyimproverespiratoryruction，thehemodynamicsismorestableandeffectis longer，whichismoresuitableforpatientsungergoingthoracicsurgery． K【eywords1penehyclidinehydrochloride；atropine；thoracicsurgery；onelungvention；respiratoryandcirculatory function ModernOncology2015，23(07)：0986—0988 摘【要】 目的：比较盐酸戊乙奎醚和阿托品用于开胸手术术前用药对呼吸和循环功能的影响。方法：80例 ASA分级I—II级全麻下行开胸手术患者 ，随机分成两组 ，P组(盐酸戊乙奎醚组)和A组 (阿托品组)，每组 4O例。每组患者麻醉诱导前分别给予盐酸戊乙奎醚