AZ91D基CaP%2f壳聚糖生物材料的制备和腐蚀行为.pdfVIP

The 6th China Corrosion Conference Preparation and Degradation Behavior of AZ91D Based CaP/ Chitosan Biological Material Jie ZHANG1,2, Changsong DAI*1, Jie WEI*1, Zhaohui WEN3 1Haerbin Institute of Technology, School of Chemistry Engineering and Technology, Haerbin, China 2Jiamusi University, Pharmaceutical College, Jiamusi, China 3 The First Affiliated Hospital of Haerbin Medical University, Haerbin, China Email: changsd@ hit.edu.cn Abstract: Magnesium and magnesium alloy have high specific strength and stiffness, with a biodegradable and biocompatible, are the ideal bone substitute materials. However, the rapid corrosion rate of magnesium and magnesium alloy, which limit their clinical application. Therefore, how to improve the magnesium and magnesium alloy corrosion resistance become a serious problem. To improve the binding force between the film and the substrate, preparation technology of CaP / chitosan coatings were studied by electrophoretic deposition (EPD) in this paper. First of all, hydroxyapatite (HA) nanoparticles were prepared by co-precipitation. Electrophoretic suspension were fabricated by mixing the acetic acid aqueous containing the chitosan and HA and ethanol liquid containing HA. The samples prepared under different conditions were immersed in phosphate buffer solution (PBS), and then immersion in simulated body fluid (m-SBF). The results show that the ceramic layer prepared under voltage 40-60v can endure the 60N load, CaP / chitosan coatings reduce the degradation rate of magnesium alloy. Keywords: magnesium alloy; hydroxyapatite; chitosan; electrophoretic deposition AZ91D 基 CaP/壳聚糖生物材料的制备及腐蚀行为