生物医药论文-雷公藤药材及制剂的HPLC指纹图谱研究.docVIP

雷公藤药材及制剂的HPLC指纹图谱研究 摘要 目的：建立药材的HPLC指纹对照测定方法：采用C18色谱柱甲醇-梯度洗脱药材指纹图谱共有模式以最接近共有模式的药材为指纹对照采用夹角余弦法分别从化学成分和含量两个方面对不同产地药材的HPLC指纹图谱进行相似性评价。结果：建立的药材指纹图谱分离好结论：以指纹对照品药材良好药材关键词：雷公藤高效液相色谱法 Tripterygium wilfordii Hook. f and tripterygium tablets by HPLC Fingerprint Chromatogram Abstract Objective: To establish a stable and repeatable HPLC reference fingerprint chromatogram standard for the quality analysis and control of Tripterygium wilfordii Hook. f. and its preparations. Methods: HPLC separation was performed on a C18 column with methanol-water as mobile phase in a gradient elution mode. The refere