细支气管肺泡癌77例临床分析.pdfVIP

旦匾壁咝盘查!!!!至!旦筮!!鲞笙!!塑!!!!墅!逝!：壁211里!竺!!!!!y!!：!!：型!：!! ·1089· ．论著． 细支气管肺泡癌77例临床分析 李芸余秉翔 【摘要】 目的探讨细支气管肺泡癌的临床症状、诊断、误诊、病理类型、影像学特点、治疗方案及预 后。方法 回顾性分析解放军总医院2003年1月至2007年12月期间住院治疗的经病理证实的77例细 支气管肺泡癌病例。结果本组病例占我院同期住院治疗的原发性支气管肺癌患者的4．6％(77／1665)， 男女比例为1．66：l；对53例资料完整病例进行统计学分析，中位生存期47．4个月；吸烟、治疗方案的组间 生存曲线差异有显著意义(Po．05)。结论细支气管肺泡癌患者临床表现多样。缺乏特征，咳大量泡沫 样痰的症状并不多见。再加上影像学上的多样性．易被溟诊；对细支气管肺泡癌的治疗应采用手术为主，结 合化疗、放疗、分子靶向治疗的综合治疗方式；对晚期不能手术的患者采用先化疗后分子靶向治疗的续贯疗 法可取得较好的疗效。 【关键词】细支气管肺泡癌；临床特点；治疗；预后 Clinical of77 withbronchioloalveolarcarcinomaLIYun，yU analysispatients Bing—xiang．Departmentof Medicine．PLAGeneral 100853．China Respiratory Hospital。Beijing Correspondingauthor：ⅢBing—xiang。Email：bingxiang—yu@hotmail．com To theclinical and [Abstract]Objectiveinvestigate characteristics，treatmentand ofbronchioloalveolarcarcinoma(BAC)．Methods radiologieal regimenprognosis 77 Theclinicaldataof BAC whowereadmittedinPLA were patients generalhospitalretrospectively Theenrolledcasesinthis accountedfor4．6％(77／1665)of with analyzed．Results study patientsprimary were in carcinomawho admittedPLA thesame ratioof bronchiogenic generalhospitalduring period．The male female was1．66：1．The was4 tO mediansurvivaltime 7．4months．Thesurvivalwas patients patients correlatedwith andtreatment Bronchorrheaisnot seeninBAC． smoking regimen．Conclusions commonly Becauseofthe and clinical be diversity radiological atypical symptom，BACmaymisdiagnosed．Surgery remainsthe treatment andmolecular