耳穴贴压配合5-HT3受体拮抗剂治疗化疗呕吐疗效观察.pdfVIP

·444· 文章编号：1005-0957(2011)07—0444一03 ·临床研究· 耳穴贴压配合5一HT3受体拮抗剂治疗化疗呕吐疗效观察 叶宇飞，李绍旦，冯宇 (中国人民解放军总医院I}|医科，北京10。853) 【摘要】 目的观察耳穴贴压对恶性肿瘤化疗引起呕叶及IL吐药所敛便秘的临床疗效。方法将47例患者随机分为治疗组 贴。结果 比较差异均具有统计学意义(必0．05，PO．01)。治疗组用药后24h内和用药24～48h内便秘发生率分别为29．6％和25．9％， 起的呕叶反应，且能减少忠嚣阏应用5一HT3受体拮抗剂造成的便秘。 【关键词】 耳穴贴压：呕叶：化疗：肿瘤 【中图分类号】 R246．1 【文献标志码】 A DOI：lO．3969／j．issn．1005一0957。2011．07。444 obser、ratio啮onthe ofAuncuIarPointPlaster 5-HT3 in E艏cacy The阳pypl吣 ReceptorAntagoIlists1hating yE地舌f，“s^口D-d册，，舢地． Chemotherapy-inducedVbmiting Genernl Hospitdl To tIleclinical ofauricular for ttlmor 【Abstract】objective efficacy plaster malignantchemotherapy— investigate point therapy induced aIl“emetic-induced were allocatedtoa仃eatment Vomitjng粕d constipation．MethodsForty-sevenpatientsrandornJy of27casesandacontrolof20cases．Thetreatment 5一HT3 andauricular group group groupwas百Ven receptoralltagonists point bean aIldmecontrol aIldnon—auricularbeafI asa plasterthempy group，5一HT3receptorantagonists point plaj；tertherapypIacebo． iIl were ResuItsT．11etotal mtesacute and 44．4％锄d thetreatment emcacy VomitingdelayedVoIIliting 62．9％，respectivelyin and15．0％and thecontrol were dif艳rencesinbothbetweenthe statisticaIly group 25．0％，respectiVely，ingroup．There significant 24hrs two incidenceof was29．6％witllinand25．9％within48量lrsaftermedicationin groups(P0．05，P0．01)．Theconstipation metreatmentand60．O％withinboth24aIld48