米索前列醇联合利多卡因用于钳刮术的临床观察.pdfVIP

维普资讯 2008年6月第46卷第18期 ·药物与临床 · 米索前列醇联合利多卡因用于钳刮术的临床观察 谢丽君 饶天全 项心怡 陈 玉 胡宗渝 (四川中医药高等专科学校附属医院，四川绵阳621000) 摘【要】目的 观察米索前列醇联合利多卡因宫旁神经阻滞麻醉在早孕钳刮术的临床疗效。方法 选择 100例自愿要求终止 8 12周妊娠的患者随机分为两组，观察组 50例术前3h121服米索前列醇 0．4mg，术前3～5min在宫颈旁4．8点钟处各注射 1％利多卡因2．5mL。对照组50例用宫颈扩张器逐号扩张宫颈后直接行钳刮术。观察两组宫颈121扩张程度、人流综合反应 发生情况、手术时间及术中出血量。结果 观察组与对照组相比，术前宫颈扩张程度高；人流综合反应发生率低；手术时间 短。出血量少，两组比较差异有显著性意义(P0．01)。结论 米索前列醇联合利多卡因宫旁神经阻滞麻醉用于早孕钳刮术效 果好，操作简单、方便，副作用小，值得临床推广。 关【键词】米索前列醇；利多卡因；钳刮术；早孕；宫旁神经阻滞麻醉 中【图分类号】R169．42 文【献标识码】A 文【章编号】1673—9701(2008)18—183—02 CHnicalObservation ofthe Effect of MisoprostolCombined with Lido- caine Before Curettage X／EI{‘L『Ⅱ1RAO TianquanXIANG CI-I~N YuH-UZongvu DepamnentofObstetricsand Gynecology．tlle Affiliated Hospitalof Sichuan CollegeofTraditional ChineseMedicine．Sichuan 621000 A【bstract1Objec~veToinvestigatetheclinicaleffectofmisoprostolcombined tlllidocaineunderuterinenerveblockanesthesia before cure,age．Methods 100 patients wiht 8～12 weeks’pregnnacy were rnadomly divided into two groups，hte 50 patients in observationgrouptookoralmisoprostol0．4mg beforecurettage．5mLof 1％ lidocainewasinjectedintohtecervixbeforeoperation．The patients in controlrgoup didn’ttake medicine．hte following bewteen htewto groups such as dilaattioh of cervix，hte syndrome of artificial abortion，operativetimenadbleedingduringoperationwereobserved．ResultsThereweremarkeddifferences(P0．01)，tlle observation group obtained bettereffectthna controlgroup，hte dilaattion of cervix Was better，hte sny dromeof artificial al~rtion Was less happening，hte operative time Was less，hte bleeding Was less．Conclusion Misopmsmlcombinde with lidocaine underuterine nerve block naesthesiahasgood effectbefore curettage，wiht convenientoperation，simple application nad less side effect．it’Sworth clinicallyof spreading． K【eyWo