蛇伤凉血合剂治疗毒蛇咬伤致急性肾损伤临床观察.pdfVIP

蛇伤凉血合剂治疗毒蛇咬伤致急性肾损伤临床观察 林坚 曾仲意 （深圳市中医院，深圳 518033 ） 【摘要】 目的 探讨中西医结合救治毒蛇咬伤所致急性肾损伤（AKI ）的临床疗效。 方法 蛇伤致 AKI 病人 49 例，随机分成 2 组：对照组（n=25 ）和治疗组（n=24 ）。对照组 给予西医常规治疗，治疗组在常规治疗的基础上加服蛇伤凉血合剂，疗程 7-14 天。结果 治 疗组少尿持续时间(5 ±3)d，对照组为(8 ±5)d，组间差异有显著意义（P ＜0.05 ）；治疗组 4 例(16%)透析治疗，对照组 10 例(41%)行透析，差异有显著意义（P ＜0.05 ）；2 组疗效比较 差异显著（P ＜0.05 ）。结论 蛇伤凉血合剂能显著提高毒蛇咬伤致 AKI 的疗效。 【关键词】 毒蛇咬伤；急性肾损伤；中医药治疗 Clinical Observation of Sheshangliangxue Mixture on Acute Kidney Injury Lin Jian, Zeng Zhongyi （Shenshen Hospitalof Traditional Chinese Medicine, Shenzhen, 518033) [Abstract] AIM To study the clinical therapeutic effect of Sheshangliangxue Mixture on acute kidney injury (AKI) caused by venomous snake bite. Methods 49 AKI patients caused by venomous snake bite were divided into 2 groups randomly :therapy group（n=25 ） and control group（n=24 ）. In therapy group ,patients were treated routinely conventional therapy with addition of Sheshangliangxue Mixture;patients in control group were given routine therapy only. The therapeutic course lasted 7-14d .Results Durations of oliguria in therapy group and control group were (5 ±3)d and (8 ±5)d respectively （P ＜0.05 ）.Hemodialysis was carried out in 4 patients(16%) of the therapy group and 10 patients(41%) of the control group ,the data showed significant difference（P ＜0.05 ）; The therapeutic effects between 2 groups have significant difference（P ＜0.05 ）.Conclusion Sheshangliangxue Mixture can improve the therapeutic effects of the patients with AKI caused by snakebite. [Keywords] Snakebite ；Acute kidney injury；TCM treatment. 毒蛇咬伤是我国南方常见急症，急性肾损伤是毒蛇咬伤的常见并发症，也是造成蛇伤 患者死亡的主要原因之一。我院蛇伤专科运用自制的中成药蛇伤凉血合剂治疗毒蛇咬伤所致 急性肾损伤，取得了较好疗效。为总结其效果，我们进行临床对照观察，现将结果报告如下。 1 临床资料与方法 1.1 病例选择 1.1.1 诊断标准 毒蛇咬伤诊断标准 ①毒蛇咬伤的病史；②患者或旁人看清楚是该种毒蛇 咬伤且所述蛇的外形符合该毒蛇特征，或带来蛇