早期血清红细胞压积、降钙素原预测重型急性胰腺炎的临床价值.pdfVIP

早期血清红细胞压积、降钙素原预测重型急 性胰腺炎的临床价值 李锦山 严宪才 缪英年 李亮 广州中医药大学附属中山中医院急诊科 【摘要】目的 探讨红细胞压积及降钙素原在重症急性胰腺炎早期识别中的临 床价值。 方法 回顾性分析因急性胰腺炎患者40例入院24小时内血清红细胞压 积(HCT)及降钙素原(PCT)水平，评价发病24小时内HCT、PCT的变化与急性胰腺炎 (AP)轻重程度的关系及其对轻重症分型的早期预测价值。其中重型急性胰腺炎组 (SAP)14例，轻型急性胰腺炎组组(SAP) 26例。应用全自动血细胞分析仪测定HCT 水平，胶体金法测定血清PCT水平。 结果 SAP组中HCT和PCT水平高于MAP组，差 异有显著性(PO.05)，HCT值(40%)判断重症急性胰腺炎的敏感性、特异性分别 为57.1％和73.1％，阳性预测值、阴性预测值分别为53.3％和76.0％。PCT值 (0.5ng/ml)判断重症急性胰腺炎的敏感性、特异性分别为92.9％和88.5％，阳 性预测值、阴性预测值分别为81.3％和95.8％。结论 HCT、PCT可作为重症急性 胰腺炎的早期识别指标。 【关键词】急性胰腺炎；红细胞压积；降钙素原； 【中图分类号】R 576 【文献标识码】A Clinical value of early measurement of hematocrit and pmcalcitonin on predicting the severity in patients with acute pancreatitis Department of Emergency, Zhongshan Hospital, Guangzhou University of TCM, Zhongshan 528400, Guangdong Province, China. [Abstract] Objective To evaluate the hematocrit (HCT) levels and pmcalcitonin (PCT) levels as early marker of severe acute pancreatitis. Methods Through retrospective analysis by 40 patients with a first acute pancreatitis episode, the HCT levels and PCT levels within 24h after admission were evaluated. The correlation between levels of HCT, PCT and the severity of patients with acute pancreatitis in early stage were investigated. Serum HCT levels was detected by Automatic blood cell analyzer. Serum PCT levels was determined by colloidal gold immunoassay (GIA) ．Results HCT and PCT levels of mild acute pancreatitis was significantly lower as compared to severe acute pancreatitis (P0.05). HCT levels(40%) in diagnosis SAP has value of sensitivity (57.1% ) and specificity ( 73.1% ) ; the positive predictive value was 53.3% and negative predictive value was 76.0%; PCT levels(0.5ng/ml) i