丁螺环酮抗抑郁增效作用临床观察.pdf

2008 6 Jun, 2008 20 11 M ed ical Journal of C inese PeoplesH ealt Vo.l 20 FHM No. 11 高传伟 (, 476000) : : 144, , , (HAMD), ( TESS) : , , , : , , ; ; ; [ ] R971. 4; R749. 41 [ ] B [] 0369( 2008) 11- 1133- 02 A Comparative Study of BuspironeS Add- effect in Treatment ofDepression GAO C uan- w ei (T e Second PeoplesHospital of S angqiu, S angqiu 476000, C ina) Abstract Objective:To explore t e add- effect of Busp irone to antidepressan ts. Methods: 144 patientsw it depressive epi sodesw ere random ly divided into two groups, treatedw it Busp irone and Im ipram ine in study group, ot er group w it only Im ipram ine, HAMD w asused to evaluate t e c anges of depression, TESS used tO evaluate side- effect. Results: In study group it as ear er effec tual tmi e and sign ificantly curative effect w ile low - dose Im ipram ine, but as little side- effects. Conclusions: Busp irone as more add- effect to an tidepressants but no s ignificantly side- effects. It as app licative value in clin icalm edicine. Key ords Busp irone; Im ipram ine; Add- efflect; S ide- efflect [ 1] , 20 mg /d, ( 150 ∃ 25. 6) mg /d; 72, , ( 250 ∃ 50) m g/d, 6, 72, 1 1. 2. 2 6 1, 1. 1 2006 2 2007 6 ( HAMD ), 246 , !∀ 3 , ( TESS) CCMD- 3 , ( HAMD) , HAMD , # 75% [ 2] 17# 18 ; ,