硫酸镁治疗新生儿缺氧缺血性脑病的临床实践和思考.pdfVIP

·16· ClinPrac 中国临床实用医学2007年11月第1卷第11期ChinaMed，Nov2007，V01．1，No．11 ·短篇论著 硫酸镁治疗新生儿缺氧缺血性脑病的 临床实践与思考 张小莉 张新华 张莉 【摘要】 治疗作用。方法 治疗组86例入院后在综合治疗的基础上给予25％硫酸镁加10％葡萄糖10～15ml静 脉滴注，2次／d，连用3d，对照组仅为综合治疗，观察两组患儿的神经系统症状持续时间，血Ca2+，血 M92+水平和神经行为测评(NBNA)分值。结果治疗组惊厥时间缩短，血Ca2+升高，NBNA分值提高， 三项指标与对照相比差异显著。结论HIE在常规治疗的基础上，早期加用硫酸镁，有助于缓解临床症 状，改善近期疗效。 【关键词】 新生儿；缺氧缺血性脑病；硫酸镁 Clinical andconsiderationon inthetreatmentofneonatal practice magnisiumsulphate hypoxic-ischemic ZHANG Chindrens encephalopathyXiao—li，ZHANGXin·Hua，ZHANG—li．Departmentofpediatrics，Shanxi Shanxi hospital 030013，China To theeffectsof onneonatal 【Abstract】Objective investigate magnesiumsulphate hypoxic．ischemic Onthebasisof casesofneonatalinfantsintreated were encephalopathy．Methods treatment，86 general group 0．2 with 10—15ml a three gived25％magnesiumsulphateml／kg 10％glucose intravenously，twiceday，for casesofneonatalinfantsincontrolreceived treatment．Thedurationof innerv- days．79 group general symptoms OU8 levelof theScoreofneonatalbehavioral system，blood assessment(NBNA) Ca2+，M92+and neurological wereobservedinthetwo Thedurationofconvulsionintreated was blood groups．Results group shorter，the levelofCa2+intreated was andthescoreofNBNAintreatedalsowas thanthosein grouphigher group higher control were differencebetweenthesetwo inthethererecords．Conclusion group．Theresignificently