外伤性尿崩症诊治体会.pdfVIP

医学临床研究　2006 年 5 月 　第 23 卷 　第 5 期 　J Clin Res , May 2006 , Vol 23 , №5 6·97 · ·论著 · 外伤性尿崩症的诊治体会 林岚 　司和平 　丁山 (汕头大学医学院第二附属医院 ,广东 　汕头 　5 1504 1) 　　[摘要]【目的】探讨颅脑损伤后尿崩症的有效治疗方案 。【方法】对 10 例颅脑损伤后尿崩症病例的临床 特征进行分析 。【结果】10 例颅脑损伤后尿崩症 ,伤后 6 ～23 d 发病 ,24 h 尿量 4 500 ～12 000 ml ,尿 比重 1. 003～1. 0 10 。采用双氢克尿噻、卡马西平等口服药物治疗疗效不明显 。长效尿崩停肌肉注射或口服弥凝治 疗 ,疗效显著 ,除 1 例失随访外均治愈 。【结论】颅脑损伤后尿崩症的临床表现典型 ,综合治疗疗效佳 ,预后好 。 　　[ 关键词] 　尿崩症/ 诊断 ; 　尿崩症/ 治疗 ; 　脑损伤/ 并发症 Cl inical Analysis on Diagnosis and Treatment of Diabetes Insipidus Af ter Craniocerebral Inj ury 　　　L I N L an , 　S I H ep i ng , 　DI N G S han ( Dep a rtment of N eu ros u rg ery , the S econ d A f f i l i ate d H osp i t al of S hantou Uni vers i ty of M e d ical S ciences , S hantou , Guang dong 5 1504 1 Chi na ) 　　[ Abstract] 【Obj ective 】To st udy t he clinical charact eri stics and t reat ment mea sures of 10 p atient s wit h dia bet es in sipidu s aft er craniocerebral inj ury . 【Met hods 】The clinical dat a of 10 p atient s wit h diabet es in sipidu s af t er caniocerebral inj ury were analyzed . 【Result s 】Diabet es in sipidu s happ ened 6～23 day s aft er t he inj ury , t he quantit y of urine was between 4 500～12 000 ml and t he sp ecific gravit y between 1. 003 and 1. 0 10 . Hydroi chlorot hiazide E or carbamazepine was not effective ,while pit ressin t annat e oil for inj ection and DDAV P were effective . The p atient s were all cured . 【Conclu sion 】The clinical charact eri stics of diabet es in sipidu s i s oft en cla ssic , t he curative effect and p ro gno si s will be goo d aft er p rop er diagno si s and t reat ment . 　　[ Key words] 　diabet esin sipidu s/ D I ; 　diabet es in sipidu s/ T H ; 　brain inj uries/ CO ( ) [ 中图分类号] 　R584 . 3 　[文献标识码] 　A