长托宁联合血液灌流治疗急性重度有机磷农药中毒的疗效观察.pdfVIP

32 ·论 著 · ~eptember2U1Z，VOI,10，NO．26 长托宁联合血液灌流治疗急性重度有机磷农药中毒的疗效观察 陈辉 民 (厦门市第三医院ICU，福建 厦~]361000) 【摘要】目的 探讨急性重度有机磷农药中毒患者采用长托宁联合血液灌流治疗的临床效果。方法 选择我院2009年 5月至2011年 5月收 治的重度有机磷农药中毒患者40例，随机分为两组，对照组20例采用长托宁治疗，观察组20例在此基础上联合血液灌流治疗，就两组 临床资料进行回顾性分析。结果 观察组治愈时间、ICU停留时间明显短于对照组，中间综合征发生率明显低于对照组，差异均有统计学 意义 (PO．05)。病死率两组比较差异无统计学意义 O．O5)。结论 临床对急性重度有机磷农药中毒患者进行治疗时，采用长托宁与 血液灌流联用，提高抢救成功率，改善惠者远期生命质量。 【关键词】长托宁；血液灌流；急性重度有机磷农药中毒 ；效果观察 中图分类号：R595．4 文献标识码：B 文章编号：1671-8194 (2012)26-0032-02 EffectofPenehyclidineHyd~ocMoHdeCom binedwith Hem operfusion inTreatm entofAcuteSevereOrganophosphorusPesticide PoisoningCurativeEffectObservation CHEN Hui．rain (DepartmentofICU,TheThirdHospitalofXiamen，Xiamen361000,Chin [Abstract]ObjectiveTostudytheacutesevere0rganophosphoruspesticidepoisoningpatientsbypenehyclidinehydrochloridecombinedwith hemoperfusionintherteatmentofclinicaleffect．MethodsInOUrhospitalfrom2009Mayto2011Mayweresevereorganophosphoruspesticidepoisoningof 40cases，wererandomlydividedintotwogroups，20casesnithecontrolgroupusingpenehyclidinehydrochloridetreatment，theobservationgroup20cases onthebasisoftheCombinedHemoperfusiontreatment，twogroupsofclinicaldatawereretrospectivelynaalyzed．ResuRsTheobservationgroupcB~etime， ICUresidencetimewassignificantlyshorterhtanthatinthecontrolgroup，intermediatesyndromeincidencewassignificantlylowerhtantheconrtolgroup， thedifferenceWasstatisticallysignificnat(PO．05)．Mortalityinhtetworgoupscomparedifferencenottohavesattisticalsingificance(PO．05)．Conclusions Theclinicalofacutesevereorgnaophosphoruspesticidepoisoningpatients，usingpenehyclidinehydrochlorideandhemoperfusioncombinedwith，increase thesuccessfulrescuerate，improvehtequalityoflifeofpatientswithlongtemr ． [Keywords